Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902221 | 0.87 | PPARA (0.47) | PPARDPPARAPPARGALDH1A1 | |
| SCHEMBL6904075 | 0.86 | PPARA (0.40) | PPARDPPARAPPARGALDH1A1 | |
| SCHEMBL3972769 | 0.86 | PPARG (0.48) | PPARDPPARAPPARG | |
| SCHEMBL6903502 | 0.83 | PPARG (0.40) | PPARDPPARAPPARG | |
| SCHEMBL6903473 | 0.83 | PPARG (0.44) | PPARDPPARAPPARG | |
| SCHEMBL3971145 | 0.81 | PPARA (0.52) | PPARDPPARAPPARGALDH1A1 | |
| SCHEMBL3971738 | 0.81 | PPARA (0.52) | PPARDPPARAPPARGALDH1A1 | |
| SCHEMBL3973894 | 0.81 | PPARA (0.52) | PPARDPPARAPPARGALDH1A1 | |
| SCHEMBL3968405 | 0.78 | PPARG (0.48) | PPARDPPARAPPARG | |
| Pemaglitazar SCHEMBL6902223 | 0.76 | PPARA (0.52) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412326-A1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011819-A1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-13 | — | — | WO | disclosed |