Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 13/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902221 | 0.89 | PPARA (0.47) | PPARGPPARAPPARDPTPN1 | |
| SCHEMBL3973311 | 0.84 | PPARG (0.54) | PPARGPPARAPTPN1 | |
| SCHEMBL6904075 | 0.84 | PPARA (0.40) | PPARGPPARAPPARDPTPN1 | |
| SCHEMBL6903479 | 0.83 | PPARD (0.39) | PPARGPPARAPPARD | |
| Pemaglitazar SCHEMBL6903499 | 0.80 | PPARG (0.45) | PPARGPPARAPPARDPTPN1 | |
| SCHEMBL3971145 | 0.80 | PPARA (0.52) | PPARGPPARAPPARDPTPN1 | |
| SCHEMBL3973894 | 0.80 | PPARA (0.52) | PPARGPPARAPPARDPTPN1 | |
| SCHEMBL3971738 | 0.80 | PPARA (0.52) | PPARGPPARAPPARDPTPN1 | |
| SCHEMBL3976202 | 0.78 | PPARG (0.51) | PPARGPPARAPPARDPTPN1 | |
| SCHEMBL11993021 | 0.78 | PPARG (0.51) | PPARGPPARAPPARDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412326-A1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011819-A1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-13 | — | — | WO | disclosed |