Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877644 | 0.98 | KDM4E (0.41) | KDM4EALDH1A1MAPTGAATP53 | |
| SCHEMBL4493171 | 0.81 | POLB (0.38) | KDM4EALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL4503380 | 0.81 | POLB (0.41) | KDM4EALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL694533 | 0.81 | POLB (0.41) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL4493176 | 0.81 | POLB (0.38) | KDM4EALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL10174373 | 0.81 | SMN1; SMN2 (0.43) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL13131163 | 0.81 | POLB (0.38) | KDM4EALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL3971854 | 0.81 | SMN1; SMN2 (0.41) | KDM4EALDH1A1POLBSMN1; SMN2MAOB | |
| SCHEMBL9417243 | 0.81 | DDB1 (0.47) | KDM4EALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL13131091 | 0.80 | POLB (0.38) | KDM4EALDH1A1MAPK1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412326-A1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011819-A1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-13 | — | — | WO | disclosed |