SCHEMBL6903620

SCHEMBL6903620

C=C(C)C.C=Cc1ccc(C)cc1.C=Cc1ccc(CBr)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TP53 P04637 3/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.39
RAB9A P51151 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
RECQL P46063 1/20 0.36
MDM2 Q00987 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1443930 0.93 ALDH1A1 (0.46) CYP3A4CYP2C9CYP2C19TP53MAPT
SCHEMBL123485 0.84 ALDH1A1 (0.55) CYP3A4CYP2C9CYP2C19TP53MAPT
SCHEMBL1270901 0.83 CYP3A4 (0.46) CYP3A4CYP2C9CYP2C19TP53MAPT
SCHEMBL6942962 0.83 CYP3A4 (0.39) CYP3A4CYP2C9CYP2C19TP53MAPT
SCHEMBL184000 0.82 ALDH1A1 (0.58) TP53MAPTMEN1KMT2AALDH1A1
SCHEMBL2849520 0.79 CYP3A4 (0.48) CYP3A4CYP2C9CYP2C19TP53MAPT
Hexane SCHEMBL28578368 0.78 CYP3A4 (0.44) CYP3A4CYP2C9CYP2C19TP53MAPT
SCHEMBL28564936 0.77 GRIK1 (0.37) CYP3A4CYP2C9CYP2C19TP53MAPT
SCHEMBL11325348 0.77 ALDH1A1 (0.50) CYP3A4CYP2C9CYP2C19TP53MAPT
SCHEMBL7672210 0.77 ALDH1A1 (0.50) CYP3A4CYP2C9CYP2C19TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6652937-B1 Nylon plastic alloy and addition polymer modifier HUTCHINSON (FR) 2003-11-25 US claimed
EP-1023161-B1 COMPOSITE THERMOPLASTIC-ELASTOMER PRODUCT HUTCHINSON (FR) 2003-10-15 EP claimed
CN-112997044-B Thermal management structure with fluid channels 哈金森公司 2023-03-17 CN disclosed
CN-112997044-A Thermal management structure with fluid channels 哈金森公司 2021-06-18 CN disclosed
EP-0946608-B1 ALKENYL SILANE FUNCTIONALIZATION OF ALKYLSTYRENE HOMOPOLYMERS AND COPOLYMERS EXXONMOBIL CHEM PATENTS INC (US) 2004-04-28 EP disclosed
US-6652937-B1 Nylon plastic alloy and addition polymer modifier HUTCHINSON (FR) 2003-11-25 US disclosed
EP-1023161-B1 COMPOSITE THERMOPLASTIC-ELASTOMER PRODUCT HUTCHINSON (FR) 2003-10-15 EP disclosed
US-6011120-A Alkenyl silane functionalization of alkylstyrene homopolyers and copolymers EXXON CHEMICAL PATENTS, INC. (US) 2000-01-04 US disclosed
EP-0946608-A1 ALKENYL SILANE FUNCTIONALIZATION OF ALKYLSTYRENE HOMOPOLYMERS AND COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 1999-10-06 EP disclosed
US-5849828-A Metalation and functionalization of polymers and copolymers EXXON CHEMICAL PATENTS INC (US) 1998-12-15 US disclosed
US-5840810-A Metalation and functionalization of polymers and copolymers EXXON CHEMICAL PATENTS INC (US) 1998-11-24 US disclosed
US-5821308-A A REACTION PRODUCT OF A COPOLYMER OF MONOISOOLEFIN AND ALKYLSTYRENE WITH A SUPERBASE AND ELECTROPHILIC REAGENT EXXON CHEMICAL PATENTS INC (US) 1998-10-13 US disclosed
WO-1998028347-A1 ALKENYL SILANE FUNCTIONALIZATION OF ALKYLSTYRENE HOMOPOLYMERS AND COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 1998-07-02 WO disclosed
EP-0842201-A1 METALATION AND FUNCTIONALIZATION OF POLYMERS AND COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 1998-05-20 EP disclosed
EP-0832138-A2 METALATION AND FUNCTIONALIZATION OF POLYMERS AND COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 1998-04-01 EP disclosed
US-5670581-A ALKALI METALLIZATION OF ISOOLEFIN-ALKYLSTYRENE COPOLYMER EXXON CHEMICAL PATENTS INC. (US) 1997-09-23 US disclosed
WO-1996040802-A1 METALATION AND FUNCTIONALIZATION OF POLYMERS AND COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 1996-12-19 WO disclosed
WO-1996036650-A2 METALATION AND FUNCTIONALIZATION OF POLYMERS AND COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 1996-11-21 WO disclosed