Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.68 |
| ▸ | DRD2 | P14416 | 8/20 | 0.68 |
| ▸ | DRD3 | P35462 | 8/20 | 0.68 |
| ▸ | DRD5 | P21918 | 7/20 | 0.68 |
| ▸ | DRD4 | P21917 | 5/20 | 0.59 |
| ▸ | METAP1 | P53582 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12595448 | 1.00 | — | — | |
| SCHEMBL6907774 | 1.00 | DRD1 (0.68) | DRD1DRD2DRD3DRD5DRD4 | |
| Ammonia Solution, Strong SCHEMBL1799116 | 0.98 | DRD1 (0.66) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL6900363 | 0.93 | DRD1 (0.74) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL4581239 | 0.88 | METAP1 (0.63) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL30777630 | 0.88 | METAP1 (0.63) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL22523888 | 0.87 | DRD2 (0.55) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL4041676 | 0.87 | METAP1 (0.58) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL4895916 | 0.83 | METAP1 (0.61) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL23835146 | 0.82 | METAP1 (0.73) | DRD1DRD2DRD3DRD5METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |