Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378873 | 0.81 | TDP1 (0.48) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL9819003 | 0.80 | HTR2A (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL4237177 | 0.80 | ALDH1A1 (0.48) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL4192867 | 0.80 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL29187623 | 0.80 | ALDH1A1 (0.48) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL4798497 | 0.80 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL4377949 | 0.76 | ANPEP (0.52) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL21582183 | 0.76 | ALDH1A1 (0.44) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL4011582 | 0.76 | TDP1 (0.48) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL3791903 | 0.76 | TDP1 (0.48) | TDP1ALDH1A1HPGDALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751105-A | Preparation method of 4-bromocyclopropylbenzene | 爱斯特（成都）生物制药股份有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-116751105-B | Preparation method of 4-bromocyclopropylbenzene | 爱斯特（成都）生物制药股份有限公司 | 2026-03-31 | — | — | CN | disclosed |
| CN-116751105-A | Preparation method of 4-bromocyclopropylbenzene | 爱斯特（成都）生物制药股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116751105-A | Preparation method of 4-bromocyclopropylbenzene | 爱斯特（成都）生物制药股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-110294680-A | A kind of preparation method in levels Moses spit of fland | 北京深蓝海生物医药科技有限公司 | 2019-10-01 | — | — | CN | disclosed |
| EP-1425002-A1 | ARYLOXYPROPYLAMINES AS CHEMOSENSITIZING AGENTS IN THE TREATMENT OF CANCER | Ramot at Tel Aviv University Ltd. (IL) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003022258-A1 | ARYLOXYPROPYLAMINES AS CHEMOSENSITIZING AGENT IN THE TREATMENT OF CANCER | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2003-03-20 | — | — | WO | disclosed |
| US-4957934-A | AROMATASE INHIBITORS, TREATMENT OF STEROID HORMONE DEPENDENT DISEASES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-09-18 | — | — | US | disclosed |
| EP-0004447-A2 | Preparation of trifluoromethylphenols and novel trifluoromethylphenyl benzyl ether intermediates | ELI LILLY AND COMPANY (US) | 1979-10-03 | — | — | EP | disclosed |