SCHEMBL6903992

SCHEMBL6903992

CC1=Cc2ccc(C)cc2C1[Zr](=C(c1ccccc1)c1ccccc1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
PKM P14618 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6905967 0.94 NPC1 (0.34) NPC1RAB9ALMNAPKM
SCHEMBL6904598 0.90 NPC1 (0.34) NPC1RAB9AMEN1LMNAKMT2A
Hydrochloric Acid SCHEMBL8380990 0.87 LMNA (0.33) MEN1LMNAKMT2A
SCHEMBL5078596 0.85 NPC1 (0.30) NPC1RAB9APDK2
SCHEMBL6904422 0.85 NPC1 (0.34) NPC1RAB9APKM
Hydrochloric Acid SCHEMBL19056232 0.84
SCHEMBL6904043 0.80 CNR2 (0.33) NPC1RAB9ALMNA
SCHEMBL6903075 0.80 NPC1 (0.34) NPC1RAB9AMEN1LMNAKMT2A
SCHEMBL6905185 0.77 MEN1 (0.30) MEN1LMNAKMT2A
SCHEMBL6904699 0.77 NPC1 (0.34) NPC1RAB9AMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed