Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 4/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.31 |
| ▸ | FLT4 | P35916 | 4/20 | 0.31 |
| ▸ | KDR | P35968 | 4/20 | 0.31 |
| ▸ | FLT3 | P36888 | 4/20 | 0.31 |
| ▸ | FLT1 | P17948 | 3/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523878 | 1.00 | ALDH1A1 (0.80) | ALDH1A1TRIM24TRIM33CDC25BCA1 | |
| SCHEMBL6898981 | 1.00 | ALDH1A1 (0.80) | ALDH1A1TRIM24TRIM33CDC25BCA1 | |
| SCHEMBL11115410 | 1.00 | ALDH1A1 (0.80) | ALDH1A1TRIM24TRIM33CDC25BCA1 | |
| SCHEMBL869650 | 1.00 | ALDH1A1 (0.80) | ALDH1A1TRIM24TRIM33CDC25BCA1 | |
| SCHEMBL4421428 | 1.00 | ALDH1A1 (0.80) | ALDH1A1TRIM24TRIM33CDC25BCA1 | |
| SCHEMBL367368 | 1.00 | — | — | |
| SCHEMBL25497698 | 1.00 | — | — | |
| SCHEMBL869649 | 1.00 | ALDH1A1 (0.80) | ALDH1A1TRIM24TRIM33CDC25BCA1 | |
| SCHEMBL4421424 | 1.00 | ALDH1A1 (0.80) | ALDH1A1TRIM24TRIM33CDC25BCA1 | |
| SCHEMBL1404279 | 1.00 | ALDH1A1 (0.80) | ALDH1A1TRIM24TRIM33CDC25BCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759557-B2 | MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-07-06 | — | — | US | disclosed |