Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28991492 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1CXCR3HDAC3 | |
| SCHEMBL12513193 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1CXCR3HDAC3 | |
| SCHEMBL8847356 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1CXCR3HDAC3 | |
| SCHEMBL4071900 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1CXCR3HDAC3 | |
| SCHEMBL1539238 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1CXCR3HDAC3 | |
| SCHEMBL5177610 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1CXCR3HDAC3 | |
| SCHEMBL2294073 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1CXCR3HDAC3 | |
| SCHEMBL3421758 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1CXCR3HDAC3 | |
| SCHEMBL7532053 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1CXCR3HDAC3 | |
| SCHEMBL869651 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1CXCR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759557-B2 | MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-07-06 | — | — | US | disclosed |