SCHEMBL7532053

SCHEMBL7532053

O=C1C/C=C\CCCCCCCCCC1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.48
TRIM33 Q9UPN9 2/20 0.48
ALDH1A1 P00352 2/20 0.48
CXCR3 P49682 1/20 0.36
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28991492 1.00 TRIM24 (0.48) TRIM24TRIM33ALDH1A1CXCR3HDAC3
SCHEMBL12513193 1.00 TRIM24 (0.48) TRIM24TRIM33ALDH1A1CXCR3HDAC3
SCHEMBL8847356 1.00 TRIM24 (0.48) TRIM24TRIM33ALDH1A1CXCR3HDAC3
SCHEMBL4071900 1.00 TRIM24 (0.48) TRIM24TRIM33ALDH1A1CXCR3HDAC3
SCHEMBL6904016 1.00 TRIM24 (0.48) TRIM24TRIM33ALDH1A1CXCR3HDAC3
SCHEMBL1539238 1.00 TRIM24 (0.48) TRIM24TRIM33ALDH1A1CXCR3HDAC3
SCHEMBL5177610 1.00 TRIM24 (0.48) TRIM24TRIM33ALDH1A1CXCR3HDAC3
SCHEMBL2294073 1.00 TRIM24 (0.48) TRIM24TRIM33ALDH1A1CXCR3HDAC3
SCHEMBL3421758 1.00 TRIM24 (0.48) TRIM24TRIM33ALDH1A1CXCR3HDAC3
SCHEMBL869651 1.00 TRIM24 (0.48) TRIM24TRIM33ALDH1A1CXCR3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4282274-A FABRIC SOFTENER ARTICLES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-08-04 US claimed
US-4250200-A Flavoring with a mixture of isochroman musk compounds INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-02-10 US claimed
US-4215006-A 2-and 3-Cyclotetradecen-1-one to augment or enhance the aroma of solid or liquid detergents INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-07-29 US claimed
US-4183965-A FLAVORS FOR FOODS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-01-15 US claimed
EP-0983989-B1 Methylcyclotetradec-5-ene-1-one GIVAUDAN SA (CH) 2002-03-27 EP disclosed
US-6326349-B1 MUSK ODOR GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2001-12-04 US disclosed
EP-0983989-A1 Methylcyclotetradec-5-ene-1-one Givaudan Roure (International) S.A. (CH) 2000-03-08 EP disclosed
US-4608193-A PERFUMES, FOODS, AROMA ENHANCERS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1986-08-26 US disclosed
US-4536299-A ENHANCING: LIQUID OR SOLID FABRIC SOFTENERS, CHEWING GUM, TOOTHPASTE, MEDICINES, CHEWING TOBACCO, COLOGNES, POWEDERS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-08-20 US disclosed
US-4525364-A FOODS, MEDICINE, COSMETICS, DETERGENTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-06-25 US disclosed
US-4522765-A Di(7-octenyl) carbonate INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-06-11 US disclosed
US-4515712-A PERFUMES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-05-07 US disclosed
US-4224352-A Pear flavoring containing a mixture of 2- and 3-cyclotetradecen-1-ones INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-09-23 US disclosed
US-4224352-A Pear flavoring containing a mixture of 2- and 3-cyclotetradecen-1-ones INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-09-23 US disclosed
US-4215006-A 2-and 3-Cyclotetradecen-1-one to augment or enhance the aroma of solid or liquid detergents INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-07-29 US disclosed
US-4215006-A 2-and 3-Cyclotetradecen-1-one to augment or enhance the aroma of solid or liquid detergents INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-07-29 US disclosed
US-4215006-A 2-and 3-Cyclotetradecen-1-one to augment or enhance the aroma of solid or liquid detergents INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-07-29 US disclosed
US-4183965-A FLAVORS FOR FOODS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-01-15 US disclosed
US-4183965-A FLAVORS FOR FOODS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-01-15 US disclosed
US-4183965-A FLAVORS FOR FOODS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-01-15 US disclosed