SCHEMBL6904405

SCHEMBL6904405

Cc1cc(C(=O)O)c(C)c(C(=O)O)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
GAA P10253 1/20 0.44
ALDH1A1 P00352 6/20 0.43
LDHA P00338 1/20 0.42
LDHB P07195 1/20 0.42
CYP3A4 P08684 1/20 0.42
ACHE P22303 1/20 0.42
NOTUM Q6P988 2/20 0.41
MAPK1 P28482 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HMGB1 P09429 1/20 0.38
CXCL12 P48061 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14989153 0.88 KDM4E (0.50) KDM4EKMT2AMEN1TDP1HPGD
SCHEMBL14989265 0.86 KDM4E (0.44) KDM4EKMT2AMEN1TDP1HPGD
SCHEMBL238022 0.85 LDHA (0.48) KDM4EKMT2AMEN1TDP1HPGD
SCHEMBL6909091 0.83 LDHA (0.47) KDM4EKMT2AMEN1TDP1HPGD
SCHEMBL6913206 0.83 LDHA (0.47) KDM4EKMT2AMEN1TDP1HPGD
SCHEMBL6913632 0.83 LDHA (0.47) KDM4EKMT2AMEN1TDP1HPGD
SCHEMBL6912920 0.83 LDHA (0.47) KDM4EKMT2AMEN1TDP1HPGD
SCHEMBL6915102 0.83 LDHA (0.47) KDM4EKMT2AMEN1TDP1HPGD
SCHEMBL6909095 0.83 LDHA (0.47) KDM4EKMT2AMEN1TDP1HPGD
SCHEMBL6915568 0.83 LDHA (0.47) KDM4EKMT2AMEN1TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100381480-C Process for preparing high-molecular aliphatic polycarbonate CHANGCHUN APPLIED CHEMISTRY (CN) 2008-04-16 CN claimed
CN-1257885-A Process for preparing high-molecular aliphatic polycarbonate CHANGCHUN APPLIED CHEMISTRY (CN) 2000-06-28 CN claimed
CN-1257753-A Process for preparing composite catalyst of rare-earth complex CHANGCHUN APPLIED CHEMISTRY (CN) 2000-06-28 CN claimed
CN-105461624-B A kind of method that sulfosalicylic acid collaboration cyclopentadienyl titanium dichloride water mutually efficiently prepares quinoline 陕西师范大学 2018-05-08 CN disclosed
CN-104185629-B cycloalkane derivatives 第三共株式会社 2017-10-13 CN disclosed
CN-105435851-B The preparation method of mesoporous composite material and catalyst and its preparation method and application and the dioxolanes of 2,2 dimethyl, 4 methyl 1,3 中国石油化工股份有限公司 2017-09-29 CN disclosed
CN-106939009-A It is a kind of to be used to treat medicine of cerebral concussion and preparation method thereof 牡丹江医学院 2017-07-11 CN disclosed
CN-105214735-B The preparation method of mesoporous composite material and catalyst and its preparation method and application and the dioxolanes of 2,2 dimethyl, 4 methyl 1,3 中国石油化工股份有限公司 2017-06-30 CN disclosed
CN-105461624-A Method for efficiently preparing quinoline derivative from titanocene dichloride in cooperation with with sulfo-benzoic acid in water phase UNIV SHAANXI NORMAL 2016-04-06 CN disclosed
CN-104672461-A Flame retardant polymers containing renewable content and making method thereof IBM 2015-06-03 CN disclosed
WO-2013149328-A1 ANION-CONDUCTING POLYMER SIMON FRASER UNIVERSITY (CA) 2013-10-10 WO disclosed
CN-100381480-C Process for preparing high-molecular aliphatic polycarbonate CHANGCHUN APPLIED CHEMISTRY (CN) 2008-04-16 CN disclosed
EP-0885930-B1 Impact-resistant polyamide compositions INVENTA AG (CH) 2004-12-22 EP disclosed
US-6831137-B2 Impact resistant transparent polyamide alloys EMS INVENTA AG (CH) 2004-12-14 US disclosed
CN-1102144-C Noval pyrimidine derivatives and prepn. processes thereof YUHAN CORP (KR) 2003-02-26 CN disclosed
US-20020128377-A1 Impact resistant transparent polyamide alloys EMS-PATENT AG (CH) 2002-09-12 US disclosed
CN-1257753-A Process for preparing composite catalyst of rare-earth complex CHANGCHUN APPLIED CHEMISTRY (CN) 2000-06-28 CN disclosed
CN-1257885-A Process for preparing high-molecular aliphatic polycarbonate CHANGCHUN APPLIED CHEMISTRY (CN) 2000-06-28 CN disclosed
EP-0885930-A1 Impact-resistant polyamide compositions EMS-INVENTA AG (CH) 1998-12-23 EP disclosed
CN-1155281-A Noval pyrimidine derivatives and prepn. processes thereof YUHAN CORP (KR) 1997-07-23 CN disclosed