Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477878 | 0.82 | POLB (0.46) | POLBNPSR1PIN1TAAR1LMNA | |
| SCHEMBL18113457 | 0.82 | PIN1 (0.45) | POLBNPSR1PIN1TAAR1LMNA | |
| SCHEMBL30603802 | 0.82 | PIN1 (0.45) | POLBNPSR1PIN1TAAR1LMNA | |
| SCHEMBL31355016 | 0.81 | PIN1 (0.47) | POLBNPSR1PIN1TAAR1LMNA | |
| SCHEMBL5530169 | 0.77 | PIN1 (0.44) | POLBNPSR1PIN1TAAR1LMNA | |
| SCHEMBL2393385 | 0.77 | TAAR1 (0.42) | POLBNPSR1PIN1TAAR1LMNA | |
| SCHEMBL8871352 | 0.77 | POLB (0.42) | POLBNPSR1PIN1TAAR1LMNA | |
| SCHEMBL7527310 | 0.76 | PIN1 (0.53) | POLBNPSR1PIN1TSHRALDH1A1 | |
| SCHEMBL21677219 | 0.76 | HDAC3 (0.41) | POLBNPSR1PIN1TAAR1LMNA | |
| SCHEMBL18683166 | 0.76 | HDAC3 (0.41) | POLBNPSR1PIN1TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002788-B1 | Process for preparing halogenated phenylmalonates | BASF AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| EP-0984919-B1 | PROCESS FOR THE PREPARATION OF ARYLMALONATES | BASF AG (DE) | 2003-01-22 | — | — | EP | disclosed |
| US-6156925-A | Process for the preparation of halogenated phenylmaloates | AMERICAN CYANAMID COMPANY (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0984919-A4 | PROCESS FOR THE PREPARATION OF ARYLMALONATES | AMERICAN CYANAMID CO (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-1002788-A1 | Process for preparing halogenated phenylmalonates | American Cyanamid Company (US) | 2000-05-24 | — | — | EP | disclosed |
| EP-0984919-A1 | PROCESS FOR THE PREPARATION OF ARYLMALONATES | AMERICAN CYANAMID COMPANY (US) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998041496-A1 | PROCESS FOR THE PREPARATION OF ARYLMALONATES | AMERICAN CYANAMID COMPANY (US) | 1998-09-24 | — | — | WO | disclosed |
| US-5756815-A | DEHALOGENATION, CARBOXYLATION WITH MAGNESIUM AND DIALKYL CARBONATE OR AN ALKYL CHLOROFORMATE FOR INHIBITING BY-PRODUCT | AMERICAN CYANAMID COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| US-5750766-A | Process for the preparation of arylmalonates | AMERICAN CYANAMID COMPANY (US) | 1998-05-12 | — | — | US | disclosed |