Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL6904889

O=C(OCCO)c1cccc(S(=O)(=O)[O-])c1C(=O)OCCO.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
TSHR P16473 8/20 0.35
TDP1 Q9NUW8 4/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
SLC7A5 Q01650 1/20 0.34
CYP3A4 P08684 3/20 0.33
MAPK1 P28482 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
TP53 P04637 2/20 0.33
LMNA P02545 2/20 0.33
NPC1 O15118 2/20 0.33
HPGD P15428 2/20 0.33
RAB9A P51151 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
GLA P06280 1/20 0.33
HIF1A Q16665 1/20 0.33
SCN1A P35498 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903317 0.81 TSHR (0.43) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Tetraphenylphosphonium SCHEMBL6905021 0.75 F2 (0.42) ALDH1A1TSHRL3MBTL1SMN1; SMN2LMNA
Tetraphenylphosphonium SCHEMBL3952278 0.75 SLC7A5 (0.47) ALDH1A1TDP1SLC7A5LMNANPC1
Tetraphenylphosphonium SCHEMBL3947421 0.74 SLC7A5 (0.41) ALDH1A1TDP1L3MBTL1SLC7A5LMNA
Potassium Ion SCHEMBL11762347 0.73 ALDH1A1 (0.59) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL5178170 0.70 ALDH1A1 (0.47) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Ethylene Glycol SCHEMBL28166871 0.70 ALDH1A1 (0.46) ALDH1A1TSHRTDP1L3MBTL1SLC7A5
SCHEMBL36533 0.69 ALDH1A1 (0.67) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL30749815 0.68 ALDH1A1 (0.64) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Potassium Ion SCHEMBL39638 0.67 ALDH1A1 (0.65) ALDH1A1TSHRTDP1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874015-B1 Process for producing aromatic polyester TEIJIN LTD (JP) 2004-02-25 EP disclosed
US-6228975-B1 MAGNETIC RECORDING MEDIA COMPRISING FILM HAVING GOOD ELECTROSTATIC ADHESION, HIGH-SPEED WINDING PROPERTIES, UNIFORM THICKNESS AND FLATNESS TEIJIN LIMITED (JP) 2001-05-08 US disclosed
US-6042773-A ESTERIFICATION IN PRESENCE OF QUATERNARY PHOSPHONIUM SULFONATE HAVING ESTER-FORMING FUNCTIONAL GROUPS TEIJIN LIMITED (JP) 2000-03-28 US disclosed
EP-0874015-A1 Process for producing aromatic polyester TEIJIN LIMITED (JP) 1998-10-28 EP disclosed