SCHEMBL6904969

SCHEMBL6904969

Clc1ccc2c(c1)Cc1ccccc1CC2

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.50
HTR2C P28335 1/20 0.50
HTR2B P41595 1/20 0.50
DRD2 P14416 11/20 0.49
DRD1 P21728 11/20 0.49
DRD5 P21918 10/20 0.49
DRD3 P35462 9/20 0.49
PNMT P11086 1/20 0.47
HSD17B3 P37058 2/20 0.46
CYP2A6 P11509 1/20 0.45
DRD4 P21917 7/20 0.44
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14102387 0.96 HTR2A (0.55) HTR2AHTR2CHTR2BDRD2DRD1
SCHEMBL31196699 0.93 HTR2A (0.45) HTR2AHTR2CHTR2BDRD2DRD1
SCHEMBL31196698 0.93 HTR2A (0.45) HTR2AHTR2CHTR2BDRD2DRD1
SCHEMBL6905658 0.93 HTR2A (0.45) HTR2AHTR2CHTR2BDRD2DRD1
SCHEMBL16559360 0.91 HTR2A (0.58) HTR2AHTR2CHTR2BPNMTHSD17B3
SCHEMBL6904514 0.86 HTR2A (0.50) HTR2AHTR2CHTR2BPNMTCYP2A6
Bromide SCHEMBL189011 0.84
Ammonia Solution, Strong SCHEMBL1325642 0.84
Hydrochloric Acid SCHEMBL8894992 0.81 HTR2A (0.46) HTR2AHTR2CHTR2BPNMTDRD4
SCHEMBL15962624 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed