SCHEMBL6905658

SCHEMBL6905658

Clc1ccc2c(c1)Cc1ccccc1C2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
HTR2B P41595 1/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
DRD2 P14416 6/20 0.44
DRD1 P21728 3/20 0.44
DRD5 P21918 2/20 0.44
DRD3 P35462 2/20 0.44
METAP1 P53582 1/20 0.44
CYP2A6 P11509 1/20 0.42
PNMT P11086 1/20 0.42
DRD4 P21917 4/20 0.41
CYP1A2 P05177 2/20 0.41
AHR P35869 2/20 0.41
CMA1 P23946 1/20 0.41
HPGD P15428 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31196699 1.00 HTR2A (0.45) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL31196698 1.00 HTR2A (0.45) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL6904969 0.93 HTR2A (0.50) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL6904514 0.92 HTR2A (0.50) HTR2AHTR2CHTR2BCA1CA2
Ammonia Solution, Strong SCHEMBL1325642 0.90
Bromide SCHEMBL189011 0.90
SCHEMBL14102387 0.89 HTR2A (0.55) HTR2AHTR2CHTR2BDRD2DRD1
Hydrochloric Acid SCHEMBL8894992 0.87 HTR2A (0.46) HTR2AHTR2CHTR2BCA1CA2
SCHEMBL1921628 0.84 KDM4E (0.59) HTR2CHTR2BCA1CA2CA4
Methylamine SCHEMBL3589883 0.83 HTR2A (0.43) HTR2AHTR2CHTR2BCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed