Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADAMTS5 | Q9UNA0 | 8/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17746120 | 0.87 | MAPT (0.47) | MAPK1ADAMTS5GFERMMP2SMN1; SMN2 | |
| SCHEMBL29748819 | 0.86 | GFER (0.63) | GFERSMN1; SMN2SLC6A7 | |
| SCHEMBL6912788 | 0.86 | GFER (0.46) | MAPK1ADAMTS5GFERMMP2SMN1; SMN2 | |
| SCHEMBL27208470 | 0.86 | GFER (0.46) | MAPK1ADAMTS5GFERMMP2SMN1; SMN2 | |
| SCHEMBL27208320 | 0.86 | GFER (0.46) | MAPK1ADAMTS5GFERMMP2SMN1; SMN2 | |
| SCHEMBL23777784 | 0.85 | ADAMTS5 (0.56) | ADAMTS5GFERMMP2SMN1; SMN2LMNA | |
| SCHEMBL23777622 | 0.85 | GFER (0.70) | MAPK1GFERSMN1; SMN2LMNAMAPT | |
| SCHEMBL23777843 | 0.85 | ADAMTS5 (0.56) | ADAMTS5GFERMMP2SMN1; SMN2LMNA | |
| SCHEMBL23777709 | 0.85 | GFER (0.70) | MAPK1GFERSMN1; SMN2LMNAMAPT | |
| SCHEMBL23777781 | 0.85 | ADAMTS5 (0.56) | ADAMTS5GFERMMP2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| US-6825200-B1 | TREATING, PROLONGING, OR EXTENDING THE ONSET OF ORGAN REJECTION IN A HUMAN DURING OR AFTER ORGAN TRANSPLANTATION IN A HUMAN | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1226159-A1 | SUBSTITUTED DIPEPTIDES HAVING NOS INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001032690-A1 | SUBSTITUTED DIPEPTIDES HAVING NOS INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-10 | — | — | WO | disclosed |