SCHEMBL6905136

SCHEMBL6905136

Cc1ccc2c(c1)C([Zr](=C(c1ccccc1)c1ccccc1)C1C=Cc3cc(-c4ccccc4)ccc31)c1cc(C)ccc1-2

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
EPHX1 P07099 1/20 0.32
CNR2 P34972 1/20 0.32
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904248 0.92 LMNA (0.34)
SCHEMBL6899167 0.91 EDNRB (0.31) POLBMAPTCTDSP1EPHX1EDNRB
SCHEMBL6903145 0.88 EDNRB (0.34) EDNRBEDNRA
SCHEMBL6905852 0.88 LMNA (0.32)
SCHEMBL6903987 0.86 BCL2 (0.37) EDNRBEDNRA
SCHEMBL6904064 0.86 LMNA (0.33)
SCHEMBL6905648 0.85 LMNA (0.31)
SCHEMBL6897163 0.84 CNR2 (0.31) CNR2
SCHEMBL6907164 0.83 LMNA (0.31) CNR2
SCHEMBL6905411 0.83 LMNA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed