Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209286 | 0.87 | KDM4E (0.55) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL6904774 | 0.87 | TDP1 (0.45) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL6904753 | 0.86 | TDP1 (0.44) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL6898723 | 0.85 | HDAC1 (0.48) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL6898018 | 0.81 | HDAC3 (0.45) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL6901597 | 0.81 | HDAC1 (0.48) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL6905067 | 0.81 | HDAC1 (0.41) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL6900931 | 0.81 | HDAC3 (0.45) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL6903079 | 0.81 | LMNA (0.50) | LMNATDP1EGFRPKMHTT | |
| SCHEMBL6903751 | 0.81 | EGFR (0.40) | HDAC1HDAC2HDAC3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417169-A2 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Bristol-Myers Squibb Pharma Company (US) | 2004-05-12 | — | — | EP | claimed |
| WO-2003016270-A2 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2003-02-27 | — | — | WO | claimed |
| EP-1417169-A2 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Bristol-Myers Squibb Pharma Company (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003016270-A2 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |