Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 4/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1904379 | 0.95 | TSHR (0.45) | CYP3A4CYP2C9CYP2C19CYP2D6TDP1 | |
| SCHEMBL11339907 | 0.88 | LMNA (0.53) | CYP3A4CYP2C9CYP2C19TDP1TSHR | |
| SCHEMBL2724325 | 0.81 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19CYP2D6TDP1 | |
| SCHEMBL8463251 | 0.81 | GAA (0.56) | CYP3A4CYP2C9CYP2C19CYP2D6TDP1 | |
| SCHEMBL11180684 | 0.79 | BCHE (0.46) | TSHRLMNA | |
| SCHEMBL11187673 | 0.77 | TSHR (0.38) | CYP3A4CYP2C9CYP2C19CYP2D6TSHR | |
| SCHEMBL11167537 | 0.76 | KDM4E (0.36) | GAAALDH1A1 | |
| SCHEMBL11451796 | 0.76 | TSHR (0.62) | CYP2C9CYP2C19TDP1TSHRKMT2A | |
| SCHEMBL11451797 | 0.76 | TSHR (0.62) | CYP2C9CYP2C19TDP1TSHRKMT2A | |
| SCHEMBL1535588 | 0.75 | GAA (0.62) | CYP3A4CYP2C9CYP2C19CYP2D6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105278009-B | Manufacturing method, hard coat film, polarizing film and the liquid crystal display device of hard coat film | 富士胶片株式会社 | 2019-01-29 | — | — | CN | disclosed |
| EP-1084183-B1 | GRANULAR FORM OF A MIXTURE OF A NICKEL-QUENCHER AND A BENZOPHENONE AND PROCESS FOR ITS PREPARATION | GREAT LAKES CHEMICAL EUROP (CH) | 2004-06-16 | — | — | EP | disclosed |
| CN-1172176-A | Phenol-free stabilization of polyolefin fibres | CIBA SC HOLDING AG (CH) | 1998-02-04 | — | — | CN | disclosed |