Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 15/20 | 0.60 |
| ▸ | ABCC8 | Q09428 | 15/20 | 0.60 |
| ▸ | KCNJ11 | Q14654 | 15/20 | 0.60 |
| ▸ | KCNJ8 | Q15842 | 15/20 | 0.60 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908807 | 0.96 | ABCC9 (0.66) | ABCC9ABCC8KCNJ11KCNJ8GPR174 | |
| SCHEMBL6431863 | 0.92 | ABCC9 (0.66) | ABCC9ABCC8KCNJ11KCNJ8GPR174 | |
| SCHEMBL6910248 | 0.88 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8GPR174 | |
| SCHEMBL6908334 | 0.84 | ABCC9 (0.55) | ABCC9ABCC8KCNJ11KCNJ8GPR174 | |
| SCHEMBL6467085 | 0.84 | ABCC9 (0.55) | ABCC9ABCC8KCNJ11KCNJ8GPR174 | |
| SCHEMBL6908767 | 0.82 | MEN1 (0.44) | ABCC9ABCC8KCNJ11KCNJ8GPR174 | |
| SCHEMBL6431947 | 0.82 | ABCC9 (0.47) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| SCHEMBL7235703 | 0.80 | ABCC9 (0.47) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| SCHEMBL6471235 | 0.80 | ABCC9 (0.67) | ABCC9ABCC8KCNJ11KCNJ8GPR174 | |
| SCHEMBL6910686 | 0.80 | ABCC9 (0.55) | ABCC9ABCC8KCNJ11KCNJ8GPR174 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040097-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2004-04-14 | — | — | EP | claimed |
| EP-1040097-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2004-04-14 | — | — | EP | disclosed |