SCHEMBL6905635

SCHEMBL6905635

CCOCCC=C(O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.35
EP300 Q09472 1/20 0.32
GRIK1 P39086 2/20 0.32
GRIK2 Q13002 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289382 0.81 ALDH1A1 (0.43) ALDH1A1TSHRTHRBEP300GRIK1
SCHEMBL33746 0.81 ALDH1A1 (0.43) ALDH1A1TSHRTHRBEP300GRIK1
SCHEMBL4278699 0.79 GRIK1 (0.41) ALDH1A1TSHRTHRBEP300GRIK1
SCHEMBL33662 0.78 ALDH1A1 (0.45) ALDH1A1TSHRTHRB
SCHEMBL289014 0.78 ALDH1A1 (0.45) ALDH1A1TSHRTHRB
SCHEMBL289016 0.78 ALDH1A1 (0.45) ALDH1A1TSHRTHRB
SCHEMBL4577548 0.78 ALDH1A1 (0.45) ALDH1A1TSHRTHRB
SCHEMBL5821019 0.78 ALDH1A1 (0.41) ALDH1A1TSHRTHRBSMN1; SMN2HCAR2
SCHEMBL6390794 0.78 ALDH1A1 (0.36) ALDH1A1TSHRTHRBGRIK1GRIK2
SCHEMBL30580 0.75 CYP2C9 (0.38) ALDH1A1TSHRSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040171867-A1 Reactive monomer composition modified by a small-amount of lactones, an acrylic polyol resin, a curable resin composition, and a coating composition OKAZAKI AKIRA (JP) 2004-09-02 US disclosed
US-6767987-B2 CURABLE RESIN COMPOSITION COMPRISING ACRYLIC POLYOL RESIN INCLUDING HYDROXYALKYL(METH)ACRYLATE COMPOSITION HAVING SMALL AMOUNT OF POLYMERIZED LACTONE MONOMER, AND MELAMINE RESIN DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-07-27 US disclosed
US-20030149227-A1 Lowly lactone-modified reactive monomer composition, acrylic polyol resins produced with the same, curable resin compositions and coating compositions DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-08-07 US disclosed
EP-1227113-A1 LOWLY LACTONE-MODIFIED REACTIVE MONOMER COMPOSITION, ACRYLIC POLYOL RESINS PRODUCED WITH THE SAME, CURABLE RESIN COMPOSITIONS AND COATING COMPOSITIONS DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2002-07-31 EP disclosed
EP-0559186-B1 Self-crosslinking resin KANSAI PAINT CO LTD (JP) 1997-09-03 EP disclosed
EP-0571991-B1 Coating resin compositions KANSAI PAINT CO LTD (JP) 1997-07-30 EP disclosed
US-5587426-A POLYURETHANES KANSAI PAINT COMPANY, LIMITED (JP) 1996-12-24 US disclosed
EP-0583777-B1 Self-crosslinking resin KANSAI PAINT CO LTD (JP) 1996-11-20 EP disclosed
EP-0519513-B1 Self-crosslinking resin KANSAI PAINT CO LTD (JP) 1996-09-11 EP disclosed
EP-0584572-B1 Self-crosslinking resin KANSAI PAINT CO LTD (JP) 1996-09-04 EP disclosed
US-5296529-A Having carboxyl group, blocked isocyanate group, hydroxyl group in molecule prepared from vinyl polymer having KANSAI PAINT COMPANY, LIMITED (JP) 1994-03-22 US disclosed
EP-0584572-A1 Self-crosslinking resin KANSAI PAINT CO., LTD. (JP) 1994-03-02 EP disclosed
EP-0583777-A1 Self-crosslinking resin KANSAI PAINT CO., LTD. (JP) 1994-02-23 EP disclosed
US-5288803-A Containing a blocked isocyanate vinyl polymer KANSAI PAINT COMPANY, LIMITED (JP) 1994-02-22 US disclosed
US-5274045-A Urethane groups from unsaturated hydroxy and isocyanate compounds KANSAI PAINT COMPANY, LIMITED (JP) 1993-12-28 US disclosed
EP-0571991-A1 Coating resin compositions KANSAI PAINT CO., LTD. (JP) 1993-12-01 EP disclosed
EP-0559186-A1 Self-crosslinking resin KANSAI PAINT CO., LTD. (JP) 1993-09-08 EP disclosed
EP-0519513-A2 Self-crosslinking resin KANSAI PAINT CO., LTD. (JP) 1992-12-23 EP disclosed
EP-0519462-A2 Self-crosslinking resin KANSAI PAINT CO., LTD. (JP) 1992-12-23 EP disclosed
EP-0502457-A1 Self-crosslinkable resin KANSAI PAINT CO., LTD. (JP) 1992-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171867-A1 Reactive monomer composition modified by a small-amount of lactones, an acrylic polyol resin, a curable resin composition, and a coating composition MSR1, FUT4, MRE11 ALDH1A1 2508/4885TSHR 1750/4885THRB 1689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.