Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 8/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424427 | 0.88 | L3MBTL1 (0.44) | L3MBTL1KAT6AGLO1SLC40A1KDM4E | |
| SCHEMBL6908900 | 0.81 | CYP2D6 (0.46) | GLO1KDM4EPKMALDH1A1TP53 | |
| SCHEMBL4427092 | 0.73 | L3MBTL1 (0.58) | L3MBTL1KAT6AGLO1SLC40A1KDM4E | |
| SCHEMBL4422634 | 0.71 | CYP2D6 (0.43) | GLO1KDM4EPKMALDH1A1TP53 | |
| SCHEMBL4425842 | 0.71 | MEN1 (0.51) | KDM4EEGFRMEN1KMT2AGAA | |
| SCHEMBL4421984 | 0.71 | EGFR (0.53) | L3MBTL1GLO1PKMEGFRALDH1A1 | |
| SCHEMBL6526208 | 0.71 | CYP2D6 (0.42) | GLO1KDM4EPKMALDH1A1TP53 | |
| SCHEMBL4421005 | 0.68 | EGFR (0.35) | EGFRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4425255 | 0.68 | EGFR (0.35) | EGFRGAA | |
| SCHEMBL4433510 | 0.68 | TSHR (0.47) | SLC40A1ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048393-A2 | NOVEL INHIBITORS OF β-LACTAMASE | METHYLGENE, INC. (CA) | 2004-06-10 | — | — | WO | disclosed |