Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 6/20 | 0.38 |
| ▸ | F3 | P13726 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5422452 | 0.79 | F7 (0.51) | F7F3F2F10PRSS1 | |
| SCHEMBL8300552 | 0.70 | F7 (0.49) | F7F3F2F10PRSS1 | |
| SCHEMBL8299398 | 0.70 | F7 (0.47) | F7F3F2F10PRSS1 | |
| SCHEMBL5882260 | 0.69 | F7 (0.58) | NPSR1SMN1; SMN2F7F3F2 | |
| SCHEMBL5044585 | 0.67 | F7 (0.75) | F7F3F2F10PRSS1 | |
| SCHEMBL5139581 | 0.67 | F7 (0.52) | F7F3F2F10PRSS1 | |
| SCHEMBL5883389 | 0.67 | F7 (0.56) | NPSR1SMN1; SMN2F7F3F2 | |
| SCHEMBL5882092 | 0.67 | F7 (0.72) | NPSR1SMN1; SMN2F7F3F2 | |
| SCHEMBL5883639 | 0.66 | F7 (0.55) | NPSR1SMN1; SMN2F7F3F2 | |
| SCHEMBL7150980 | 0.66 | F7 (0.74) | F7F3F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242585-A1 | Acylsulfamide inhibitors of factor VIIa | GENENTECH, INC. | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242585-A1 | Acylsulfamide inhibitors of factor VIIa | TFPI, TFPI2, HABP2 | TNF 2990/4885NPSR1 2025/4885SMN1; SMN2 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.