SCHEMBL6905969

SCHEMBL6905969

O=P(O)(O)COCC(CCO)n1cnc2c(Cl)ncnc21

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.51
HPRT1 P00492 5/20 0.48
FGFR1 P11362 2/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
DGAT1 O75907 1/20 0.39
HDAC6 Q9UBN7 1/20 0.37
P2RX7 Q99572 2/20 0.37
FGFR4 P22455 1/20 0.36
CYP3A4 P08684 1/20 0.36
ENPP1 P22413 2/20 0.36
ENPP3 O14638 1/20 0.36
AHCY P23526 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6898237 0.87 FGFR1 (0.56) HPRT1FGFR1SLC22A6CYP3A4ENPP1
SCHEMBL6687661 0.87 HPRT1 (0.48) FDPSHPRT1FGFR1SLC22A6CYP3A4
SCHEMBL6904563 0.87 HPRT1 (0.48) FDPSHPRT1FGFR1SLC22A6CYP3A4
SCHEMBL6897528 0.87 HPRT1 (0.48) FDPSHPRT1FGFR1SLC22A6CYP3A4
SCHEMBL6899488 0.86 HPRT1 (0.47) FDPSHPRT1FGFR1SLC22A6CYP3A4
SCHEMBL6899073 0.84 FDPS (0.51) FDPSHPRT1FGFR1SLC22A6DGAT1
SCHEMBL6690025 0.84 HPRT1 (0.46) HPRT1FGFR1SLC22A6CYP3A4
SCHEMBL6693987 0.84 HPRT1 (0.46) FDPSHPRT1FGFR1SLC22A6CYP3A4
SCHEMBL6905054 0.83 HPRT1 (0.45) HPRT1FGFR1SLC22A6P2RX7FGFR4
SCHEMBL6903285 0.83 HPRT1 (0.45) FDPSHPRT1FGFR1SLC22A6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040014722-A1 Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases BIOCRYST PHARMACEUTICALS, INC. 2004-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014722-A1 Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases NSUN2, POLR2H, NSUN3 FDPS 3139/4885HPRT1 871/4885FGFR1 2799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.