Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604812 | 0.75 | — | — | |
| SCHEMBL15380931 | 0.73 | MEN1 (0.42) | POLBMEN1KMT2ATAAR1MAPT | |
| SCHEMBL2231249 | 0.71 | POLB (0.44) | POLBMEN1KMT2ATAAR1MAPT | |
| SCHEMBL2282586 | 0.70 | TAAR1 (0.59) | POLBMEN1KMT2ATAAR1MAPT | |
| SCHEMBL2580017 | 0.70 | SCN2A (0.63) | — | |
| SCHEMBL29155145 | 0.67 | CDC7 (0.44) | GAAPRKCDPIM1CDK2CDK1 | |
| SCHEMBL994128 | 0.67 | MEN1 (0.50) | POLBMEN1KMT2ATAAR1MAPT | |
| SCHEMBL2281476 | 0.67 | MEN1 (0.50) | POLBMEN1KMT2ATAAR1MAPT | |
| SCHEMBL11275747 | 0.67 | POLB (0.46) | POLBMEN1KMT2ATAAR1MAPT | |
| SCHEMBL10502996 | 0.66 | MEN1 (0.45) | POLBMEN1KMT2ATAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453518-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DISORDERS OF NON-HUMAN MAMMALS | Boehringer Ingelheim International GmbH (DE) | 2004-09-08 | — | — | EP | disclosed |
| US-20030162796-A1 | Pharmaceutical composition for the treatment of disorders of non-human mammals | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2003-08-28 | — | — | US | disclosed |
| WO-2003030910-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DISORDERS OF NON-HUMAN MAMMALS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2003-04-17 | — | — | WO | disclosed |
| EP-1300146-A1 | Pharmaceutical composition for the treatment of animal mammary tumors | Boehringer Ingelheim International GmbH (DE) | 2003-04-09 | — | — | EP | disclosed |
| EP-1297184-A1 | METHOD FOR MONITORING THE EFFECT OF CANCER THERAPIES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2003-04-02 | — | — | EP | disclosed |
| US-20020102685-A1 | Novel use of inhibitors of the epidermal growth factor receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2002-08-01 | — | — | US | disclosed |
| US-20020042072-A1 | Method for monitoring the effect of cancer therapies | BOEHRINGER INGELHEIM GMBH (DE) | 2002-04-11 | — | — | US | disclosed |
| WO-2002002120-A1 | NOVEL USE OF INHIBITORS OF THE EPIDERMAL GROWTH FACTOR RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2002-01-10 | — | — | WO | disclosed |
| EP-1170378-A1 | Method for monitoring the effect of cancer therapies | Boehringer Ingelheim International GmbH (DE) | 2002-01-09 | — | — | EP | disclosed |
| EP-1170011-A1 | Novel use of inhibitors of the epidermal growth factor receptor | Boehringer Ingelheim International GmbH (DE) | 2002-01-09 | — | — | EP | disclosed |
| WO-2002000925-A1 | METHOD FOR MONITORING THE EFFECT OF CANCER THERAPIES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2002-01-03 | — | — | WO | disclosed |