Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27987567 | 0.91 | ALDH1A1 (0.53) | ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL295042 | 0.89 | ALDH1A1 (0.78) | ALDH1A1ADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL6928111 | 0.84 | ALDH1A1 (0.70) | ALDH1A1ADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL27456970 | 0.84 | ALDH1A1 (0.59) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL3391 | 0.84 | ALDH1A1 (0.70) | ALDH1A1ADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL1866116 | 0.84 | ALDH1A1 (0.70) | ALDH1A1ADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL1866113 | 0.84 | ALDH1A1 (0.70) | ALDH1A1ADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL26947493 | 0.82 | ALDH1A1 (0.68) | ALDH1A1ADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL20515564 | 0.82 | ALDH1A1 (0.68) | ALDH1A1ADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL13573486 | 0.82 | ALDH1A1 (0.68) | ALDH1A1ADRB2ADRB1ADRB3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6682916-B2 | CHEMICAL INTERMEDIATE FOR DRUGS; REDUCTION USING ENZYME | KANEKA CORPORATION (JP) | 2004-01-27 | — | — | US | disclosed |
| EP-1298119-A1 | CHLOROHYDROXYACETONE DERIVATIVE AND PROCESS FOR PRODUCING OPTICALLY ACTIVE CHLOROPROPANEDIOL DERIVATIVE FROM THE SAME | KANEKA CORPORATION (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-20020160398-A1 | Chlorohydroxyacetone derivative and process for producing optically active chloropropanediol derivative from the same | KANEKA CORPORATION (JP) | 2002-10-31 | — | — | US | disclosed |