Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142635 | 0.81 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TP53TSHRSMN1; SMN2 | |
| SCHEMBL26785 | 0.81 | MIF (0.47) | MIFALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL5465655 | 0.81 | MIF (0.47) | MIFALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| Cyclohexane SCHEMBL28419555 | 0.79 | MIF (0.43) | MIFALDH1A1CYP3A4SMN1; SMN2HIF1A | |
| Water SCHEMBL28905301 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TP53TSHRSMN1; SMN2 | |
| SCHEMBL22471928 | 0.79 | MIF (0.46) | MIFALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL28048374 | 0.79 | MIF (0.46) | MIFALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| Water SCHEMBL14972890 | 0.79 | MIF (0.46) | MIFALDH1A1CYP3A4SMN1; SMN2HIF1A | |
| SCHEMBL6437951 | 0.77 | MIF (0.44) | MIFALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL31506359 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TP53TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742244-B1 | Durable polysulfide composition for optical material | MITSUI CHEMICALS INC (JP) | 2004-08-11 | — | — | EP | disclosed |
| US-5955206-A | POLYTHIOETHERS AND ACRYLATE OR VINYL GROUPS FOR CURING TO FORM OPTICAL LENSES | MITSUI CHEMICALS, INC. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0742244-A2 | Durable polysulfide composition for optical material | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-11-13 | — | — | EP | disclosed |