Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19882662 | 1.00 | KMT2A (0.37) | KMT2ATHRBMEN1ACHEEPHX1 | |
| SCHEMBL21771088 | 1.00 | KMT2A (0.37) | KMT2ATHRBMEN1ACHEEPHX1 | |
| SCHEMBL13980435 | 1.00 | KMT2A (0.37) | KMT2ATHRBMEN1ACHEEPHX1 | |
| SCHEMBL19301949 | 1.00 | KMT2A (0.37) | KMT2ATHRBMEN1ACHEEPHX1 | |
| SCHEMBL18616072 | 1.00 | KMT2A (0.37) | KMT2ATHRBMEN1ACHEEPHX1 | |
| Cyclohexylamine SCHEMBL23883677 | 1.00 | KMT2A (0.37) | KMT2ATHRBMEN1ACHEEPHX1 | |
| SCHEMBL19301943 | 1.00 | KMT2A (0.37) | KMT2ATHRBMEN1ACHEEPHX1 | |
| SCHEMBL20836937 | 0.97 | KMT2A (0.35) | KMT2ATHRBMEN1ACHEEPHX1 | |
| SCHEMBL20983759 | 0.97 | KMT2A (0.35) | KMT2ATHRBMEN1ACHEEPHX1 | |
| SCHEMBL21090064 | 0.97 | KMT2A (0.35) | KMT2ATHRBMEN1ACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201605-A1 | HETEROARYL SUBSTITUTED PIPERIDINES | HOFFMANN-LA ROCHE, INC. | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201605-A1 | HETEROARYL SUBSTITUTED PIPERIDINES | APP, HPGDS, PSEN1 | KMT2A 739/4885THRB 2696/4885MEN1 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.