Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905033 | 0.88 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL6905073 | 0.82 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL6399972 | 0.82 | AKR1C3 (0.40) | AKR1C3AKR1C2MAPK13MAPK12MAPK11 | |
| SCHEMBL6905065 | 0.80 | AKR1C3 (0.49) | AKR1C3AKR1C2MAPK13MAPK12MAPK11 | |
| SCHEMBL6402370 | 0.79 | MAPK14 (0.57) | AKR1C3AKR1C2MAPK13MAPK12MAPK11 | |
| SCHEMBL6905074 | 0.79 | MAPK13 (0.50) | AKR1C3AKR1C2MAPK13MAPK12MAPK11 | |
| SCHEMBL7646956 | 0.78 | AKR1C3 (0.46) | AKR1C3AKR1C2MAPK13MAPK12MAPK11 | |
| SCHEMBL6900408 | 0.78 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL7198684 | 0.76 | AKR1C3 (0.53) | AKR1C3AKR1C2MAPK13MAPK12MAPK11 | |
| SCHEMBL6903356 | 0.76 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202959-B1 | AMINOBENZOPHENONES AS INHIBITORS OF IL-1-BETA AND TNF-ALPHA | LEO PHARMA AS (DK) | 2004-09-29 | — | — | EP | claimed |