Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 10/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905033 | 0.85 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL6395887 | 0.82 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL6904569 | 0.81 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL6396132 | 0.80 | MAPK14 (0.70) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL6906583 | 0.78 | AKR1C3 (0.42) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL6903356 | 0.77 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL6904590 | 0.77 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL7195744 | 0.77 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL6905074 | 0.77 | MAPK13 (0.50) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL6905073 | 0.76 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202959-B1 | AMINOBENZOPHENONES AS INHIBITORS OF IL-1-BETA AND TNF-ALPHA | LEO PHARMA AS (DK) | 2004-09-29 | — | — | EP | claimed |