SCHEMBL6907004

SCHEMBL6907004

CCCC1(OC(=O)/C=C\C(=O)O)CC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.47
ATM Q13315 1/20 0.33
TSHR P16473 2/20 0.32
TP53 P04637 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
EGLN3 Q9H6Z9 1/20 0.32
ALDH1A1 P00352 2/20 0.32
ALOX15 P16050 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17047297 0.82 HCAR2 (0.46) HCAR2ATM
SCHEMBL17047299 0.82 HCAR2 (0.46) HCAR2ATM
SCHEMBL294983 0.80 HCAR2 (0.35) HCAR2ALDH1A1
SCHEMBL18940870 0.79 HCAR2 (0.46) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL18940869 0.79 HCAR2 (0.46) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL18940873 0.79 HCAR2 (0.46) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL48742 0.78 TSHR (0.41) TSHRTP53ALDH1A1HSD17B10
SCHEMBL1524442 0.77 HCAR2 (0.44) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1402168 0.77 HCAR2 (0.44) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1402169 0.77 HCAR2 (0.44) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040214948-A1 Polyamide composition for molding HAYASHI RYUICHI (JP) 2004-10-28 US disclosed
US-20040102560-A1 Polyamide compositions for molding NOZAKI MASAHIRO (JP) 2004-05-27 US disclosed
US-20030134980-A1 Polyamide composition for molding HAYASHI RYUICHI (JP) 2003-07-17 US disclosed
WO-2000024830-A9 POLYAMIDE COMPOSITION FOR MOLDING DU PONT (US) 2001-12-06 WO disclosed
EP-1137713-A1 POLYAMIDE COMPOSITION FOR MOLDING E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-10-04 EP disclosed
EP-0734422-B1 POLYAMIDE RESIN COMPOSITION AND PRODUCTION PROCESS DU PONT (US) 2001-07-11 EP disclosed
WO-2000024830-A1 POLYAMIDE COMPOSITION FOR MOLDING E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-04 WO disclosed
US-5856428-A Crystalline aromatic polyamide resin composition E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-05 US disclosed
US-5770679-A ELASTOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-23 US disclosed
EP-0272695-B2 Tough high melt flow polyamides DU PONT (US) 1997-07-02 EP disclosed
EP-0734422-A4 POLYAMIDE RESIN COMPOSITION AND PRODUCTION PROCESS DU PONT (US) 1996-11-20 EP disclosed
EP-0734422-A1 POLYAMIDE RESIN COMPOSITION AND PRODUCTION PROCESS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-10-02 EP disclosed
WO-1995016750-A1 POLYAMIDE RESIN COMPOSITION AND PRODUCTION PROCESS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-06-22 WO disclosed
US-5274033-A Blending a polyamide and toughener and another polyamide to form a matrix; transamidation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-28 US disclosed
US-5112908-A Thermoplastic blend with low molecular weight polyamide with endcapping groups E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-12 US disclosed
EP-0272695-A2 Tough high melt flow polyamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-06-29 EP disclosed
EP-0073036-B1 TOUGHENED POLYAMIDE BLENDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-06 EP disclosed
US-4410661-A AMORPHOUS, CRYSTAL STRUCTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-10-18 US disclosed
US-4174358-A Tough thermoplastic nylon compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-11-13 US disclosed
US-4172859-A Tough thermoplastic polyester compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-10-30 US disclosed