SCHEMBL48742

SCHEMBL48742

C=CC(=O)OC1(CCC)CC1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.41
HPGD P15428 1/20 0.41
THRB P10828 3/20 0.35
ALDH1A1 P00352 4/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2938659 0.93 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL5154743 0.91 TSHR (0.38) TSHRHPGDTHRB
SCHEMBL1397188 0.91 TSHR (0.38) TSHRHPGDTHRB
Methacrylic Acid SCHEMBL9182083 0.90 HPGD (0.35) TSHRHPGDTHRB
SCHEMBL8585258 0.89 TSHR (0.47) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL1764291 0.89 HPGD (0.34) TSHRHPGD
SCHEMBL15348655 0.89 TSHR (0.57) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL27776896 0.88 TSHR (0.36) TSHRHPGDTHRB
SCHEMBL15353323 0.87 HPGD (0.33) TSHRHPGD
SCHEMBL2290619 0.87 TSHR (0.46) TSHRHPGDTHRBALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6274 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325308-A High-water-resistance Jie Gaixing glass fiber reinforced PBT engineering plastic and preparation method thereof 康辉新材料科技有限公司 2024-07-12 CN claimed
CN-118307870-A 110KV and above semiconductor shielding material and preparation method thereof 万华化学(宁波)有限公司 2024-07-09 CN claimed
US-20240218602-A1 BARRIER LAYER FOR CELLULOSE SUBSTRATE COATEX (FR) 2024-07-04 US claimed
CN-118234793-A Stabilizer based on syringic acid, vanillic acid, isovanillic acid or 5-hydroxyveratric acid, plastic composition, method for stabilizing a plastic composition and stabilizer composition 弗劳恩霍夫应用研究促进协会 2024-06-21 CN claimed
CN-114196158-B Laser carving master batch with luminous effect color marks and preparation method thereof 浙江普利特新材料有限公司 2024-06-18 CN claimed
CN-118185305-A HTPA-based high-strength composite material and production process thereof 东莞和兴新材料科技有限公司 2024-06-14 CN claimed
CN-118185299-A Polyamide/polyolefin composite material and preparation method and application thereof 武汉金发科技有限公司 2024-06-14 CN claimed
CN-118201775-A Printed packaging material with improved recyclability, recycling method and method for evaluating recyclability 康斯坦蒂亚皮尔克有限责任两合公司 2024-06-14 CN claimed
CN-118165400-A 220KV and above semiconductor shielding material and preparation method thereof 万华化学(宁波)有限公司 2024-06-11 CN claimed
CN-118146585-A Semiconductive shielding material, preparation method thereof, semiconductive shielding product and cable 北京怀柔实验室 2024-06-07 CN claimed
EP-0292251-A2 Aromatic polyester composition and process for producing the same TORAY INDUSTRIES, INC. (JP) 1988-11-23 EP claimed
US-4783511-A SUBSTITUTED SILANE WITH HYDROLYSABLE RADICALS EMS-INVENTA AG (CH) 1988-11-08 US claimed
US-4778856-A OIL SWELL RESISTANCE; COLD RESISTANCE; POND LINERS, ROOFING MEMBRANES, CABLE COVERINGS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-10-18 US claimed
US-4753992-A SILANE-CONTAINING POLYMER CROSSLINKABLE WITH WATER; ADDITION POLYMER WITH CARBOXYL GROUPS BRIDGED WITH ORGANOTIN AS CATALYST BP CHEMICALS LIMITED 1988-06-28 US claimed
EP-0107796-B1 OPTICAL FIRE-RESISTANT TELECOMMUNICATION CABLE AEG KABEL Aktiengesellschaft (DE) 1987-07-22 EP claimed
US-4680328-A Insect resistant polyethylene composition suitable for wire and cable applications THE DOW CHEMICAL COMPANY (US) 1987-07-14 US claimed
EP-0073027-B1 MASTERBATCH COMPOSITION COMPRISING A MATRIX HAVING A POLYSILOXANE DISPERSED THEREIN AND A METHOD FOR THE PREPARATION THEREOF UNION CARBIDE CORPORATION (US) 1987-05-06 EP claimed
EP-0207627-A2 Polymer composition BP Chemicals Limited (GB) 1987-01-07 EP claimed
EP-0073027-A2 Masterbatch composition comprising a matrix having a polysiloxane dispersed therein and a method for the preparation thereof UNION CARBIDE CORPORATION (US) 1983-03-02 EP claimed
US-4369289-A PROTECTIVE COATINGS UNION CARBIDE CORPORATION (US) 1983-01-18 US claimed