Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 11/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007367 | 0.84 | VCAM1 (0.40) | VCAM1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL8336610 | 0.82 | VCAM1 (0.45) | VCAM1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL29732475 | 0.79 | CYP1A2 (0.47) | VCAM1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL716507 | 0.79 | CYP1A2 (0.47) | VCAM1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL10454396 | 0.79 | GAA (0.48) | VCAM1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL4654670 | 0.79 | VCAM1 (0.54) | VCAM1CA2CA1ALDH1A1LMNA | |
| SCHEMBL8378081 | 0.78 | VCAM1 (0.49) | VCAM1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8380059 | 0.78 | VCAM1 (0.49) | VCAM1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11780531 | 0.78 | VCAM1 (0.49) | VCAM1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8380055 | 0.78 | VCAM1 (0.49) | VCAM1CYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740707-B2 | POLYPHENYLENE SULFIDE RESIN AND AN OLEFIN BASED RESIN; EXCELLENT FUEL PERMEATION RESISTANCE, AND EXCELLENT SHOCK IMPACT RESISTANCE AND HEAT RESISTANCE. | TOYODA GOSEI CO., LTD. (JP) | 2004-05-25 | — | — | US | disclosed |
| US-20030027931-A1 | Polyphenylene sulfide resin and an olefin based resin; excellent fuel permeation resistance, and excellent shock impact resistance and heat resistance. | TORAY INDUSTRIES INC. (JP) | 2003-02-06 | — | — | US | disclosed |