Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CASP7 | P55210 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2573803 | 0.79 | CYP3A4 (0.56) | RXRACYP3A4MEN1KMT2AGLA | |
| SCHEMBL16901794 | 0.76 | CYP3A4 (0.41) | RXRACYP3A4MEN1KMT2AGLA | |
| SCHEMBL8116892 | 0.75 | CYP2C9 (0.49) | CYP3A4MEN1KMT2AGLAHDAC4 | |
| SCHEMBL6747789 | 0.73 | CYP3A4 (0.48) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL25964843 | 0.73 | CYP3A4 (0.44) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL22149253 | 0.73 | MEN1 (0.44) | RXRACYP3A4MEN1KMT2AGLA | |
| SCHEMBL22149723 | 0.73 | MEN1 (0.44) | RXRACYP3A4MEN1KMT2AGLA | |
| SCHEMBL22149728 | 0.73 | CYP3A4 (0.44) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL8886719 | 0.71 | CYP3A4 (0.50) | CYP3A4MEN1KMT2AGLAHSD17B3 | |
| SCHEMBL6177937 | 0.71 | MEN1 (0.41) | CYP3A4MEN1KMT2AGLAHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018552-A1 | USE OF COMPOSITIONS CONTAINING 4-HYDROXY-2-PYRONES FOR STABILISING ORGANIC PLASTICS CONTAINING HALOGEN | REAGENS DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | WO | disclosed |
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| CN-1236357-A | Aminomethylene derivatives and ultraviolet absorber comprising the same | CHEMIPRO KASEI KAISHA LTD (JP) | 1999-11-24 | — | — | CN | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |