Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 9/20 | 0.73 |
| ▸ | MAOA | P21397 | 11/20 | 0.69 |
| ▸ | FASN | P49327 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | SI | P14410 | 4/20 | 0.61 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30346426 | 1.00 | MGAM (0.73) | MGAMMAOAFASNALDH1A1MAPT | |
| SCHEMBL30786757 | 0.93 | MGAM (0.84) | MGAMMAOAFASNALDH1A1MAPT | |
| SCHEMBL15918267 | 0.93 | MGAM (0.84) | MGAMMAOAFASNALDH1A1MAPT | |
| SCHEMBL30346436 | 0.89 | MAOA (0.69) | MGAMMAOAFASNALDH1A1MAPT | |
| SCHEMBL5446446 | 0.89 | MAOA (0.69) | MGAMMAOAFASNALDH1A1MAPT | |
| SCHEMBL30346299 | 0.86 | MGAM (0.62) | MGAMMAOAFASNALDH1A1MAPT | |
| SCHEMBL28990260 | 0.86 | MGAM (0.62) | MGAMMAOAFASNALDH1A1MAPT | |
| SCHEMBL20356594 | 0.84 | MAOA (0.67) | MGAMMAOAALDH1A1MAPTKDM4E | |
| SCHEMBL29405133 | 0.84 | MGAM (1.00) | MGAMMAOAFASNALDH1A1MAPT | |
| SCHEMBL996402 | 0.84 | MGAM (1.00) | MGAMMAOAFASNALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5176854-A | Xanthone Derivatives | HITACHI, LTD. (JP) | 1993-01-05 | — | — | US | claimed |
| CN-109369599-B | Xanthone compound and preparation method and application thereof | 广州医科大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-107602522-B | Xanthone-NO donor compound, preparation method thereof and application thereof in preparation of antitumor drugs | 暨南大学 | 2019-12-24 | — | — | CN | disclosed |
| CN-102516219-B | Halogenated polyhydroxy xanthene derivatives, preparation method and use thereof | UNIV SHENYANG PHARMACEUTICAL | 2014-12-03 | — | — | CN | disclosed |
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |
| EP-0315140-B1 | Non-linear optical device | HITACHI LTD (JP) | 1995-08-23 | — | — | EP | disclosed |
| US-5176854-A | Xanthone Derivatives | HITACHI, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0315140-A2 | Non-linear optical device | HITACHI, LTD. (JP) | 1989-05-10 | — | — | EP | disclosed |