Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156660 | 0.74 | GABRA1 (0.52) | GABRA1GABRB2TSHRPOLBALDH1A1 | |
| SCHEMBL18262837 | 0.74 | GABRA1 (0.58) | GABRA1GABRB2TSHRPOLBALDH1A1 | |
| SCHEMBL6687058 | 0.73 | GABRA1 (0.50) | GABRA1GABRB2TSHRPOLBALDH1A1 | |
| SCHEMBL301684 | 0.73 | GABRA1 (0.56) | GABRA1GABRB2TSHRPOLBCRHBP | |
| SCHEMBL3993342 | 0.71 | GABRA1 (0.48) | GABRA1GABRB2TSHRPOLBALDH1A1 | |
| SCHEMBL5918821 | 0.71 | GABRA1 (0.54) | GABRA1GABRB2TSHRPOLBCRHBP | |
| SCHEMBL36796 | 0.71 | GABRA1 (0.60) | GABRA1GABRB2TSHRPOLBCRHBP | |
| SCHEMBL27854739 | 0.69 | GABRA1 (0.52) | GABRA1GABRB2TSHRPOLBCRHBP | |
| SCHEMBL3987454 | 0.69 | GABRA1 (0.46) | GABRA1GABRB2TSHRPOLBCRHBP | |
| SCHEMBL12995993 | 0.67 | GABRA1 (0.60) | GABRA1GABRB2TSHRPOLBCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171864-A1 | Fluorinated aromatics | AFF1, AFF2, AFF4 | GABRA1 2475/4885GABRB2 3846/4885TSHR 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.