O-Tolylamine

O-Tolylamine

SCHEMBL6907330

Cc1ccccc1N.OB(O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.75
TDP1 Q9NUW8 5/20 0.75
CD44 P16070 1/20 0.50
TSHR P16473 6/20 0.45
ALOX15 P16050 2/20 0.45
CASP1 P29466 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CASP7 P55210 1/20 0.45
ACHE P22303 1/20 0.45
PIK3CA P42336 1/20 0.43
PKM P14618 1/20 0.40
ALDH1A1 P00352 7/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Tolylamine SCHEMBL27889556 1.00 CYP3A4 (0.75) CYP3A4TDP1CD44TSHRALOX15
O-Tolylamine SCHEMBL27715579 0.97 CYP3A4 (0.71) CYP3A4TDP1CD44TSHRALOX15
O-Tolylamine SCHEMBL9613766 0.89 CYP3A4 (0.94) CYP3A4TDP1CD44TSHRALOX15
O-Tolylamine SCHEMBL29441724 0.89
O-Tolylamine SCHEMBL8469060 0.89 CYP3A4 (0.94) CYP3A4TDP1CD44TSHRALOX15
O-Tolylamine SCHEMBL15789 0.89
O-Tolylamine SCHEMBL31145800 0.89
O-Tolylamine SCHEMBL11231934 0.86 CYP3A4 (0.88) CYP3A4TDP1CD44TSHRALOX15
O-Tolylamine SCHEMBL8602819 0.86
O-Tolylamine SCHEMBL21494153 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102686615-B Process for production of syndiotactic alpha-olefin polymer MITSU CHEMICALS INC 2014-05-28 CN disclosed
CN-102686615-A Process for production of syndiotactic alpha-olefin polymer MITSUI CHEMICALS INC 2012-09-19 CN disclosed
US-20040116520-A1 Anti-stress agents AMATO PHARMACEUTICAL PRODUCTS, LTD. (JP) 2004-06-17 US disclosed
EP-1362594-A1 ANTI-STRESS AGENTS AMATO PHARMACEUTICAL PRODUCTS, LTD. (JP) 2003-11-19 EP disclosed
US-4435566-A HYPOGLYCEMIA, ANTIHISTAMINE, ANTIDIABETIC ACTIVITY MARUKO SEIYAKU CO., LTD. (JP) 1984-03-06 US disclosed
US-4238491-A Method for treating hypertension with methylreserpate NIPPON CHEMIPHAR CO., LTD. (JP) 1980-12-09 US disclosed