Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7061610 | 0.95 | CA4 (0.39) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL28946762 | 0.95 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL251417 | 0.94 | CA4 (0.46) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL28305966 | 0.94 | CA4 (0.46) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL15249 | 0.94 | — | — | |
| Bicarbonate SCHEMBL18420704 | 0.94 | CA4 (0.46) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL14562609 | 0.89 | — | — | |
| Bicarbonate SCHEMBL7174903 | 0.89 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL8995977 | 0.89 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL6907373 | 0.89 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116747861-A | Layered porous copper-aluminum-magnesium catalyst and preparation method and application thereof | 上海陕煤高新技术研究院有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-117800374-A | Method for synthesizing magnesium-aluminum hydrotalcite | 江苏极易新材料有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-116747861-A | Layered porous copper-aluminum-magnesium catalyst and preparation method and application thereof | 上海陕煤高新技术研究院有限公司 | 2023-09-15 | — | — | CN | disclosed |
| US-6835364-B2 | Anionic clays for use in catalyst formulations | AKZO NOBEL N.V. (NL) | 2004-12-28 | — | — | US | disclosed |
| EP-1358148-A1 | QUASI-CRYSTALLINE HYDRATED MAGNESIUM-ALUMINIUM HYDROXY CARBOXYLATES, THEIR PREPARATION AND THEIR USE | Akzo Nobel N.V. (NL) | 2003-11-05 | — | — | EP | disclosed |
| US-20020168313-A1 | Quasi-crystalline carboxylates | ALBEMARLE NETHERLANDS B.V. (NL) | 2002-11-14 | — | — | US | disclosed |
| WO-2002072526-A1 | QUASI-CRYSTALLINE HYDRATED MAGNESIUM-ALUMINIUM HYDROXY CARBOXYLATES, THEIR PREPARATION AND THEIR USE | AKZO NOBEL N.V. (NL) | 2002-09-19 | — | — | WO | disclosed |
| CN-1145924-A | Composition based on beta-diketones and acetylacetonates for chlorine-containing polymers | RHONE POULENC CHIMIE (FR) | 1997-03-26 | — | — | CN | disclosed |
| EP-0288723-B1 | FLEXIBLE, DEEP-DRAWNABLE PLASTIC RESIN FILM FOR AUTOMOBILES FORMED OF SEVERAL LAYERS | ALKOR GMBH KUNSTSTOFFE (DE) | 1993-09-29 | — | — | EP | disclosed |
| US-5169967-A | ALUMINUM MAGNESIUM HYDROXY FATTY ACID COMPOUNDS AND THERMOSTABLE LIPOGELS INCLUDING SAME | GIULINI CHEMIE GMBH (DE) | 1992-12-08 | — | — | US | disclosed |
| EP-0117289-B1 | BASIC MAGNESIUM-ALUMINIUM-HYDROXYCARBONATE | Giulini Chemie GmbH (DE) | 1988-06-29 | — | — | EP | disclosed |
| EP-0117289-A2 | Basic magnesium-aluminium-hydroxycarbonate | Giulini Chemie GmbH (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0117289-A2 | Basic magnesium-aluminium-hydroxycarbonate | Giulini Chemie GmbH (DE) | 1984-09-05 | — | — | EP | disclosed |