Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7062462 | 0.95 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL176208 | 0.95 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL6907379 | 0.95 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL28364963 | 0.90 | CA4 (0.39) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL21638664 | 0.90 | CA4 (0.39) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL873152 | 0.90 | CA4 (0.39) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL2454268 | 0.90 | — | — | |
| Bicarbonate SCHEMBL21734207 | 0.90 | — | — | |
| Bicarbonate SCHEMBL28946762 | 0.90 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL29171483 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115175958-A | Polyolefin compositions | 巴斯夫欧洲公司 | 2022-10-11 | — | — | CN | claimed |
| CN-113166468-A | Polypropylene composition | 巴斯夫欧洲公司 | 2021-07-23 | — | — | CN | claimed |
| CN-110809600-A | Polyethylene pipe | 巴斯夫欧洲公司 | 2020-02-18 | — | — | CN | claimed |
| CN-1304351-C | Quasi-crystalline hydrated magnesium-aluminium hydroxy carboxylates, their preparation and their use | AKZO NOBEL NV (NL) | 2007-03-14 | — | — | CN | claimed |
| US-6835364-B2 | Anionic clays for use in catalyst formulations | AKZO NOBEL N.V. (NL) | 2004-12-28 | — | — | US | claimed |
| CN-1491202-A | Quasi-crystalline hydrated magnesium-aluminium hydroxy carboxylates, their preparation and their use | ŵ�����˹ɷ�����˾ | 2004-04-21 | — | — | CN | claimed |
| US-20020168313-A1 | Quasi-crystalline carboxylates | ALBEMARLE NETHERLANDS B.V. (NL) | 2002-11-14 | — | — | US | claimed |
| CN-1304351-C | Quasi-crystalline hydrated magnesium-aluminium hydroxy carboxylates, their preparation and their use | AKZO NOBEL NV (NL) | 2007-03-14 | — | — | CN | disclosed |
| CN-1304351-C | Quasi-crystalline hydrated magnesium-aluminium hydroxy carboxylates, their preparation and their use | AKZO NOBEL NV (NL) | 2007-03-14 | — | — | CN | disclosed |
| CN-1304351-C | Quasi-crystalline hydrated magnesium-aluminium hydroxy carboxylates, their preparation and their use | AKZO NOBEL NV (NL) | 2007-03-14 | — | — | CN | disclosed |
| US-6835364-B2 | Anionic clays for use in catalyst formulations | AKZO NOBEL N.V. (NL) | 2004-12-28 | — | — | US | disclosed |
| US-6835364-B2 | Anionic clays for use in catalyst formulations | AKZO NOBEL N.V. (NL) | 2004-12-28 | — | — | US | disclosed |
| CN-1491202-A | Quasi-crystalline hydrated magnesium-aluminium hydroxy carboxylates, their preparation and their use | ŵ�����˹ɷ�����˾ | 2004-04-21 | — | — | CN | disclosed |
| CN-1491202-A | Quasi-crystalline hydrated magnesium-aluminium hydroxy carboxylates, their preparation and their use | ŵ�����˹ɷ�����˾ | 2004-04-21 | — | — | CN | disclosed |
| EP-1358148-A1 | QUASI-CRYSTALLINE HYDRATED MAGNESIUM-ALUMINIUM HYDROXY CARBOXYLATES, THEIR PREPARATION AND THEIR USE | Akzo Nobel N.V. (NL) | 2003-11-05 | — | — | EP | disclosed |
| EP-1358148-A1 | QUASI-CRYSTALLINE HYDRATED MAGNESIUM-ALUMINIUM HYDROXY CARBOXYLATES, THEIR PREPARATION AND THEIR USE | Akzo Nobel N.V. (NL) | 2003-11-05 | — | — | EP | disclosed |
| US-20020168313-A1 | Quasi-crystalline carboxylates | ALBEMARLE NETHERLANDS B.V. (NL) | 2002-11-14 | — | — | US | disclosed |
| US-20020168313-A1 | Quasi-crystalline carboxylates | ALBEMARLE NETHERLANDS B.V. (NL) | 2002-11-14 | — | — | US | disclosed |
| WO-2002072526-A1 | QUASI-CRYSTALLINE HYDRATED MAGNESIUM-ALUMINIUM HYDROXY CARBOXYLATES, THEIR PREPARATION AND THEIR USE | AKZO NOBEL N.V. (NL) | 2002-09-19 | — | — | WO | disclosed |
| WO-2002072526-A1 | QUASI-CRYSTALLINE HYDRATED MAGNESIUM-ALUMINIUM HYDROXY CARBOXYLATES, THEIR PREPARATION AND THEIR USE | AKZO NOBEL N.V. (NL) | 2002-09-19 | — | — | WO | disclosed |