Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269453 | 0.86 | CYP2C19 (0.57) | CYP2C19LMNAHSD17B10SMN1; SMN2CYP2D6 | |
| SCHEMBL667322 | 0.84 | CYP2C19 (0.62) | CYP2C19LMNAHSD17B10SMN1; SMN2GRIK1 | |
| SCHEMBL11117064 | 0.83 | CYP2C19 (0.49) | CYP2C19LMNAHSD17B10SMN1; SMN2CYP2D6 | |
| SCHEMBL1716761 | 0.83 | CYP2C19 (0.49) | CYP2C19LMNAHSD17B10SMN1; SMN2CYP2D6 | |
| SCHEMBL1716759 | 0.83 | CYP2C19 (0.49) | CYP2C19LMNAHSD17B10SMN1; SMN2CYP2D6 | |
| SCHEMBL11071970 | 0.81 | CYP2C19 (0.56) | CYP2C19LMNAHSD17B10SMN1; SMN2CYP2D6 | |
| SCHEMBL17730949 | 0.80 | CYP2C19 (0.62) | CYP2C19LMNASMN1; SMN2CYP2D6SRC | |
| SCHEMBL845836 | 0.80 | CYP2C19 (0.62) | CYP2C19LMNASMN1; SMN2CYP2D6SRC | |
| SCHEMBL17730952 | 0.80 | CYP2C19 (0.62) | CYP2C19LMNASMN1; SMN2CYP2D6SRC | |
| SCHEMBL3253010 | 0.79 | CYP2C19 (0.61) | CYP2C19LMNASMN1; SMN2GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720450-B2 | USING SUCH AS 7-CYCLOHEXYL-(4,5-METHANO)HEPTANOIC ACID; CONTROLLING BLOOD INGESTING INSECTS | NORTH CAROLINA STATE UNIVERSITY | 2004-04-13 | — | — | US | disclosed |
| US-20030149103-A1 | Pesticidal activity of functionalized cyclopropanes | NORTH CAROLINA STATE UNIVERSITY | 2003-08-07 | — | — | US | disclosed |
| WO-2003051118-A1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED CYCLOPROPANES | NORTH CAROLINA STATE UNIVERSITY (US) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149103-A1 | Pesticidal activity of functionalized cyclopropanes | DDT, PPIF, CYP4F3 | CYP2C19 283/4885LMNA 3689/4885HSD17B10 1853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.