SCHEMBL6907446

SCHEMBL6907446

CC(Cc1cccc2ccccc12)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.59
KDM4E B2RXH2 2/20 0.56
APAF1 O14727 1/20 0.56
POLB P06746 1/20 0.56
MAPT P10636 1/20 0.56
RECQL P46063 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
TDP1 Q9NUW8 2/20 0.56
MMP9 P14780 2/20 0.55
MMP8 P22894 1/20 0.55
MMP14 P50281 1/20 0.55
MME P08473 2/20 0.54
ACE P12821 2/20 0.54
CPA1 P15085 1/20 0.54
ACE2 Q9BYF1 1/20 0.54
HRH4 Q9H3N8 1/20 0.49
KMT2A Q03164 1/20 0.49
ALDH1A1 P00352 1/20 0.49
SLC1A3 P43003 1/20 0.49
SLC1A2 P43004 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16017641 1.00 CTNNB1 (0.59) CTNNB1KDM4EAPAF1POLBMAPT
SCHEMBL25846959 1.00 CTNNB1 (0.59) CTNNB1KDM4EAPAF1POLBMAPT
SCHEMBL3146178 0.87 KDM4E (0.51) CTNNB1KDM4EAPAF1POLBMAPT
SCHEMBL10421147 0.87 CTNNB1 (0.54) CTNNB1KDM4EAPAF1POLBMAPT
SCHEMBL16743938 0.86 CTNNB1 (0.55) CTNNB1KDM4EL3MBTL1TDP1MMP9
SCHEMBL6623784 0.86 CTNNB1 (0.55) CTNNB1KDM4EL3MBTL1TDP1MMP9
SCHEMBL13879137 0.86 CTNNB1 (0.55) CTNNB1KDM4EL3MBTL1TDP1MMP9
SCHEMBL8874713 0.85 CTNNB1 (0.54) CTNNB1KDM4EL3MBTL1TDP1MMP9
SCHEMBL1284854 0.85 CTNNB1 (0.54) CTNNB1L3MBTL1TDP1MMP9MMP8
SCHEMBL7272663 0.84 CTNNB1 (0.75) CTNNB1MAPTTDP1MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019201749-A1 HOME HORTICULTURE SYSTEM SIGNIFY HOLDING B.V. (NL) 2019-10-24 WO disclosed
US-20130123465-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS SEATTLE GENETICS, INC. (US) 2013-05-16 US disclosed
EP-0813554-B1 METHOD FOR PRODUCING A PREPOLYMERIZED CATALYST EXXONMOBIL CHEM PATENTS INC (US) 2004-04-07 EP disclosed
US-6391817-B1 MIXING METALLOCENE CATALYST, ALPHA-OLEFIN MONOMER, HYDROGEN TO PREPOLYMERIZE; RECOVERING ANTIFOULING, ANTIAGGLOMERATING SYSTEM; CATALYST SUPPORT DOES NOT CONCURRENTLY INCLUDE TITANIUM, MAGNESIUM AND HALOGEN EXXONMOBIL CHEMICAL PATENTS INC. 2002-05-21 US disclosed
CN-1073589-C Applications of isotactic polypropylene, processes and products thereof EXXON MOBILE CHEMICAL PATENTS (US) 2001-10-24 CN disclosed
CN-1069707-C Novel polyolefin fibers and their fabrics EXXON CHEMICAL PATENTS INC (US) 2001-08-15 CN disclosed
US-6010588-A MELT PROCESSING USING CATALYST; FORMING FIBER; DRAWING EXXON CHEMICAL PATENTS INC. (US) 2000-01-04 US disclosed
US-5932669-A HOMO OR COPOLYMERIZING OLEFIN IN PRESENCE OF TRANSITIONAL METAL COMPOUND AS A METALLOCENE CATALYST AND ALUMINOXANE AS COCATALYST TARGOR GMBH (DE) 1999-08-03 US disclosed
WO-1994028034-A9 SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF EXXON CHEMICAL PATENTS INC (US) 1999-07-29 WO disclosed
CN-1043474-C Supported metallocene catalyst systems for polymerization of olefins, preparation and use thereof EXXON CHEMICAL PATENTS INC (US) 1999-05-26 CN disclosed
EP-0549900-B1 Metallocenes containing benzocondensed indenyl derivatives as ligands, process for their preparation and their use as catalysts HOECHST AG (DE) 1996-08-21 EP disclosed
CN-1128055-A Novel polyolefin fiber and fabric thereof EXXON CHEMICAL PATENTS INC (US) 1996-07-31 CN disclosed
EP-0705281-A1 SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF EXXON CHEMICAL PATENTS INC. (US) 1996-04-10 EP disclosed
US-5468440-A Forming structure from polypropylene resin produced using metallocene catalyst, orienting structure by applying stress at temperature 20-35 degrees C. above Heat Distortion Test value of polypropylene EXXON CHEMICAL PATENTS INC. (US) 1995-11-21 US disclosed
WO-1995030708-A1 APPLICATIONS OF ISOTACTIC POLYPROPYLENE, PROCESSES AND PRODUCTS THEREOF EXXON CHEMICAL PATENTS, INC. (US) 1995-11-16 WO disclosed
US-5455366-A Olefin polymerization catalysts HOECHST AG (DE) 1995-10-03 US disclosed
WO-1995018809-A1 USE OF GEL-FREE ALUMOXANE SOLUTION EXXON CHEMICAL PATENTS INC. (US) 1995-07-13 WO disclosed
WO-1994028034-A1 SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF EXXON CHEMICAL PATENTS INC. (US) 1994-12-08 WO disclosed
EP-0549900-A1 Metallocenes containing benzocondensed indenyl derivatives as ligands, process for their preparation and their use as catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-07 EP disclosed
EP-0278158-A2 Renin inhibitors containing phenylalanyl-histidine replacements MERCK & CO. INC. (US) 1988-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123465-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS MMAB, PTMS, DNPEP CTNNB1 4813/4885KDM4E 648/4885APAF1 557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.