Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3629865 | 0.84 | KDM4E (0.33) | KDM4EMAPTHPGDUSP2TP53 | |
| SCHEMBL9862758 | 0.78 | LMNA (0.35) | KDM4EMAPTHPGDUSP2TP53 | |
| SCHEMBL2811184 | 0.77 | MAPT (0.37) | KDM4EMAPTHPGDUSP2TP53 | |
| SCHEMBL5913004 | 0.74 | KDM4E (0.34) | KDM4EMAPTHPGDUSP2TP53 | |
| SCHEMBL2812126 | 0.72 | MAPT (0.36) | KDM4EMAPTHPGDUSP2TP53 | |
| SCHEMBL8033694 | 0.72 | MAPT (0.36) | KDM4EMAPTHPGDUSP2TP53 | |
| SCHEMBL121414 | 0.71 | ESR1 (0.42) | MAPTLMNAALOX12ALDH1A1 | |
| SCHEMBL7034905 | 0.71 | TSHR (0.36) | KDM4EMAPTHPGDUSP2TP53 | |
| SCHEMBL247510 | 0.71 | ESR1 (0.33) | MAPTALDH1A1 | |
| SCHEMBL5373913 | 0.71 | ESR1 (0.33) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448572-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003040157-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |