Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | RHOA | P61586 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907716 | 1.00 | GRM1 (0.49) | GRM1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL6907721 | 0.94 | GRM1 (0.42) | GRM1ALDH1A1MAPTRAB9ALMNA | |
| SCHEMBL7232085 | 0.89 | GRM1 (0.61) | GRM1ALDH1A1MAPTHPGDRAB9A | |
| Hydrochloric Acid SCHEMBL6908261 | 0.85 | MAPT (0.51) | GRM1ALDH1A1MAPTHPGDRAB9A | |
| Hydrochloric Acid SCHEMBL6908265 | 0.85 | MAPT (0.51) | GRM1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL6901288 | 0.83 | GRM1 (0.47) | GRM1ALDH1A1MAPTHPGDHRH3 | |
| SCHEMBL6901283 | 0.83 | GRM1 (0.47) | GRM1ALDH1A1MAPTHPGDHRH3 | |
| SCHEMBL7232093 | 0.81 | GRM1 (0.54) | GRM1ALDH1A1MAPTHPGDRAB9A | |
| Hydrochloric Acid SCHEMBL6908268 | 0.79 | MAPT (0.44) | GRM1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL7232091 | 0.78 | ATM (0.47) | GRM1ALDH1A1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087608-A1 | Pharmaceuticals for neuropathic pain | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2004-05-06 | — | — | US | disclosed |
| US-6664283-B1 | Pharmaceuticals for neurogenic pain | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1205187-A1 | REMEDIES FOR NEUROGENIC PAINS | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |