Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232156 | 0.82 | LMNA (0.44) | LMNARAB9AMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL7235507 | 0.82 | MAPT (0.42) | LMNARAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6904603 | 0.81 | ATM (0.46) | ATMLMNARAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7240261 | 0.80 | GRM1 (0.47) | LMNARAB9AALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL7233122 | 0.80 | GRM1 (0.46) | LMNARAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7232085 | 0.79 | GRM1 (0.61) | LMNARAB9AMEN1KMT2APOLB | |
| SCHEMBL6907716 | 0.78 | GRM1 (0.49) | LMNARAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6907720 | 0.78 | GRM1 (0.49) | LMNARAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7238022 | 0.77 | NPC1 (0.42) | LMNARAB9AALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL7234112 | 0.76 | NPC1 (0.42) | LMNARAB9AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642264-B1 | Thiazolo(3,2-a)benzoimidazole derivatives act specifically on metabotropic glutamate receptors and are used as medicaments. | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1167369-A1 | NOVEL THIAZOLOBENZIMIDAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |