Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.49 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665692 | 0.88 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL4416693 | 0.88 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL4416695 | 0.88 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL13985849 | 0.86 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL4961219 | 0.86 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL3228018 | 0.86 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL27338577 | 0.85 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL29096010 | 0.85 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL4957634 | 0.85 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL27852179 | 0.83 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103073492-A | Synthesis method of 2-(3-(S)-(3-(2-7-chlorine-2-quinolyl) vinyl) phenyl)-3-hydroxypropyl) benzoate | SHANGHAI INST ORGANIC CHEM | 2013-05-01 | — | — | CN | claimed |
| CN-103073492-A | Synthesis method of 2-(3-(S)-(3-(2-7-chlorine-2-quinolyl) vinyl) phenyl)-3-hydroxypropyl) benzoate | SHANGHAI INST ORGANIC CHEM | 2013-05-01 | — | — | CN | disclosed |
| EP-2203557-B1 | KETOREDUCTASE POLYPEPTIDES AND USES THEREOF | CODEXIS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2203557-A1 | KETOREDUCTASE POLYPEPTIDES AND USES THEREOF | Codexis, Inc. (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009042984-A1 | KETOREDUCTASE POLYPEPTIDES AND USES THEREOF | CODEXIS, INC. (US) | 2009-04-02 | — | — | WO | disclosed |