Linolenic Acid

Linolenic Acid

SCHEMBL6908141

CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)O.COc1cc(C=O)ccc1O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
MAPT P10636 4/20 0.56
HPGD P15428 4/20 0.56
F7 P08709 3/20 0.56
F3 P13726 3/20 0.56
CYP19A1 P11511 3/20 0.56
KMT2A Q03164 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
MEN1 O00255 2/20 0.56
CYP3A4 P08684 2/20 0.56
OXER1 Q8TDS5 2/20 0.56
PTGS1 P23219 2/20 0.56
PPARG P37231 2/20 0.56
PPARD Q03181 2/20 0.56
PPARA Q07869 2/20 0.56
KDM4E B2RXH2 2/20 0.56
FFAR1 O14842 1/20 0.56
NR1I2 O75469 1/20 0.56
LMNA P02545 1/20 0.56
PLA2G1B P04054 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Linoleic Acid SCHEMBL3155308 0.94 CNR1 (0.58) ALDH1A1MAPTHPGDF7F3
Oleic Acid SCHEMBL28164028 0.91 TRPV1 (0.59) ALDH1A1MAPTHPGDKMT2ATDP1
Oleic Acid SCHEMBL891276 0.91 TRPV1 (0.59) ALDH1A1MAPTHPGDKMT2ATDP1
Vanillin SCHEMBL27603751 0.87 ALDH1A1 (0.71) ALDH1A1MAPTHPGDF3KMT2A
Stearic Acid SCHEMBL891657 0.85 ALDH1A1 (0.64) ALDH1A1HPGDTDP1CYP3A4ALOX15
Palmitic Acid SCHEMBL891192 0.85 ALDH1A1 (0.64) ALDH1A1HPGDTDP1CYP3A4ALOX15
Dodecanoate SCHEMBL891292 0.85 ALDH1A1 (0.64) ALDH1A1HPGDTDP1CYP3A4ALOX15
Nonanoate SCHEMBL28996453 0.85 ALDH1A1 (0.64) ALDH1A1HPGDTDP1CYP3A4ALOX15
Vanillin SCHEMBL891409 0.84 ALDH1A1 (0.66) ALDH1A1HPGDTDP1CYP3A4KDM4E
Vanillin SCHEMBL30530333 0.83 ALDH1A1 (0.73) ALDH1A1MAPTHPGDF3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040005344-A1 Head lice formulation MUNRO DEBRA (AU) 2004-01-08 US disclosed
WO-2002036138-A1 A HEAD LICE FORMULATION EMERALD FOREST PHARMACEUTICALS PTY LTD (AU) 2002-05-10 WO disclosed