Methacrylic Acid

Methacrylic Acid

SCHEMBL6908387

C=C(C)C(=O)O.C=C(C=Cc1ccccc1)C(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.60
GLA P06280 1/20 0.60
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
HDAC3 O15379 2/20 0.53
HDAC4 P56524 2/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC6 Q9UBN7 2/20 0.53
PLIN1 O60240 2/20 0.53
LMNA P02545 2/20 0.53
RECQL P46063 2/20 0.53
PLIN5 Q00G26 2/20 0.53
ABHD5 Q8WTS1 2/20 0.53
F3 P13726 2/20 0.53
TNKS O95271 1/20 0.53
HCAR2 Q8TDS4 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC10 Q969S8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15120 0.92 MAPT (0.61) TDP1GLAALDH1A1MAPTHDAC3
SCHEMBL376003 0.92 MAPT (0.61) TDP1GLAALDH1A1MAPTHDAC3
SCHEMBL16268784 0.90 MAPT (0.59) TDP1GLAALDH1A1MAPTHDAC3
SCHEMBL28287153 0.90 MAPT (0.59) TDP1GLAALDH1A1MAPTHDAC3
Ammonia Solution, Strong SCHEMBL5175448 0.90 MAPT (0.59) TDP1GLAALDH1A1MAPTHDAC3
(Z)-1,2-Diphenylethene SCHEMBL3017350 0.86 GLA (0.59) TDP1GLAALDH1A1MAPTHDAC3
(Z)-1,2-Diphenylethene SCHEMBL9983047 0.86 GLA (0.59) TDP1GLAALDH1A1MAPTHDAC3
(Z)-1,2-Diphenylethene SCHEMBL3017352 0.86 GLA (0.59) TDP1GLAALDH1A1MAPTHDAC3
Methacrylic Acid SCHEMBL29048486 0.85 TDP1 (0.60) TDP1GLAALDH1A1MAPTHDAC3
Acrylic Acid SCHEMBL7095658 0.85 HDAC3 (0.59) TDP1GLAALDH1A1MAPTHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828368-B2 Useful for the preparation of a heat-sensitive tacky adhesive having excellent adhesive strength and blocking resistance; solid plasticizer DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-07 US disclosed
EP-1298121-A1 BIS(CIS-3,3,5-TRIMETHYLCYCLOHEXYL) PHTHALATE, PROCESS FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION Daicel Chemical Industries, Ltd. (JP) 2003-04-02 EP disclosed
US-20020193482-A1 Bis(cis-3,3,5-trimethylcyclohexyl) phthalate, process for producing the same, and thermoplastic resin composition DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-12-19 US disclosed
US-5001045-A Silver halide color photographic material containing sparingly water soluble epoxy compound and organic soluble polymer FUJI PHOTO FILM CO., LTD. (JP) 1991-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193482-A1 Bis(cis-3,3,5-trimethylcyclohexyl) phthalate, process for producing the same, and thermoplastic resin composition PSMA3, CDH1, DPY30 TDP1 2932/4885GLA 4703/4885ALDH1A1 2057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.