⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008732 | 0.73 | — | — | |
| SCHEMBL5904175 | 0.71 | CRBN (0.37) | — | |
| SCHEMBL584157 | 0.69 | — | — | |
| SCHEMBL1289696 | 0.69 | — | — | |
| SCHEMBL5253568 | 0.67 | — | — | |
| SCHEMBL2400452 | 0.67 | — | — | |
| SCHEMBL22969638 | 0.67 | — | — | |
| SCHEMBL77107 | 0.67 | — | — | |
| SCHEMBL1163501 | 0.67 | — | — | |
| SCHEMBL182943 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815183-B1 | Plasmodium sp. chitinase | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2004-11-09 | — | — | US | disclosed |
| WO-2000073488-A9 | PLASMODIUM SP. CHITINASE | UNIV TEXAS (US) | 2002-04-18 | — | — | WO | disclosed |
| WO-2000073488-A1 | PLASMODIUM SP. CHITINASE | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-12-07 | — | — | WO | disclosed |