Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7939477 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL6908960 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL3894364 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL4800699 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL1477060 | 0.58 | — | — | |
| SCHEMBL28414010 | 0.56 | — | — | |
| Hydrochloric Acid SCHEMBL617836 | 0.56 | — | — | |
| Hydrochloric Acid SCHEMBL6812899 | 0.54 | — | — | |
| Hydrochloric Acid SCHEMBL7934786 | 0.54 | — | — | |
| Hydrochloric Acid SCHEMBL7543766 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6617407-B1 | Olefin polymerization catalyst components. | THE DOW CHEMICAL COMPANY | 2003-09-09 | — | — | US | disclosed |
| EP-1177198-B1 | BIS(N,N-DIHYDROCARBYLAMINO)- SUBSTITUTED CYCLOPENTADIENES AND METAL COMPLEXES THEREOF | DOW GLOBAL TECHNOLOGIES INC (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-1177198-A1 | BIS(N,N-DIHYDROCARBYLAMINO)- SUBSTITUTED CYCLOPENTADIENES AND METAL COMPLEXES THEREOF | THE DOW CHEMICAL COMPANY (US) | 2002-02-06 | — | — | EP | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |
| WO-2000066596-A1 | BIS(N,N-DIHYDROCARBYLAMINO)- SUBSTITUTED CYCLOPENTADIENES AND METAL COMPLEXES THEREOF | THE DOW CHEMICAL COMPANY (US) | 2000-11-09 | — | — | WO | disclosed |
| EP-1021454-A1 | 2-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998006728-A1 | 2-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |