Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1194186 | 0.99 | ALDH1A1 (0.53) | ALDH1A1LMNAHPGDNFKB1NFKB2 | |
| SCHEMBL6230315 | 0.90 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDNFKB1NFKB2 | |
| Bromide SCHEMBL1193914 | 0.89 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDNFKB1NFKB2 | |
| SCHEMBL6228373 | 0.86 | ALDH1A1 (0.61) | ALDH1A1LMNAHPGDRAB9ANPC1 | |
| Bromide SCHEMBL1194085 | 0.85 | ALDH1A1 (0.64) | ALDH1A1LMNAHPGDRAB9ANPC1 | |
| Bromide SCHEMBL7201734 | 0.85 | NPC1 (0.56) | ALDH1A1LMNAHPGDRAB9ANPC1 | |
| SCHEMBL6227338 | 0.78 | NPSR1 (0.60) | ALDH1A1LMNAHPGDRAB9ANPC1 | |
| SCHEMBL6227945 | 0.78 | HPGD (0.52) | ALDH1A1LMNAHPGDRAB9ANPC1 | |
| SCHEMBL13100724 | 0.77 | HPGD (0.74) | ALDH1A1LMNAHPGDRAB9ANPC1 | |
| Bromide SCHEMBL1194184 | 0.77 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222171-B1 | PYRIDINIUM DERIVATIVES FOR THE MANAGEMENT OF AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | TORRENT PHARMACEUTICALS LTD (IN) | 2004-02-25 | — | — | EP | claimed |